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Assessment of the Effects of Levosimendan and Nigella Sativa on Myocardial Ischemia Reperfusion Injury in Rats
Ozer, Abdullah; Kilic, Yigit; Sezen, Saban Cem; Kucuk, Aysegul; Mardin, Baris; Alkan, Metin; Oktar, Levent (Gazi Univ, Fac Med, 2018)Objective: Ischemia-reperfusion injury is a chain of events put in place by tissue ischemia. Reperfusion following the damage of cell causes an active inflammatory response. In our research we tried to evaluate the protective ... -
Assessment of the effects of levosimendan and thymoquinone on lung injury after myocardial ischemia reperfusion in rats
Sezen, Saban Cem; Kucuk, Aysegul; Ozer, Abdullah; Kilic, Yigit; Mardin, Baris; Alkan, Metin; Tosun, Murat (Dove Medical Press Ltd, 2018)Aim: The aim of this study was to investigate the effects of levosimendan and thymoquinone (TQ) on lung injury after myocardial ischemia/reperfusion (I/R). Materials and methods: Twenty-four Wistar albino rats were included ... -
Effect of different doses of pregabalin on erythrocyte deformability in rats with lower limb ischemia reperfusion injury
Ozer, Abdullah; Comu, Faruk Metin; Demirtas, Huseyin; Kilic, Yigit; Mardin, Baris; Ozturk, Levent; Kucuk, Aysegul (Anaesthesia Pain & Intensive Care, 2017)Background & Objective: Acute ischemia reperfusion (IR) injury observed in the lower extremities occurs especially when a temporary cross-clamp is applied to the abdominal aorta during aortic surgery. Preoperative pregabalin ... -
Protective effect of erdosteine on erythrocyte deformability in a rat model of lower limb ischemia/reperfusion injury
Ozer, Abdullah; Demirtas, Huseyin; Comu, Faruk Metin; Erer, Dilek; Kilic, Yigit; Mardin, Baris; Oktar, G. Levent (Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: The protective effect of erdosteine on local and distant organ injury due to ischemia/reperfusion has been well documented but its effect on erythrocyte deformability needs further investigation. Our aim ...