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Toplam kayıt 50, listelenen: 1-10
Anti-Epidermal Growth Factor Receptor Aptamer and Antibody Conjugated SPIONs Targeted to Breast Cancer Cells: A Comparative Approach
(Amer Scientific Publishers, 2017)
Cancer is still one of the major reasons of illness and death throughout the world. Wide range of cancer types occur in many organs like breast, liver, lung, colon etc. The surface characteristics of these cells change, ...
Synthesis, characterization and modification of Gum Arabic microgels for hemocompatibility and antimicrobial studies
(Elsevier Sci Ltd, 2017)
Gum Arabic (GA) microgels were successfully prepared via reverse micellization method with high yield (78.5 +/- 5.0%) in 5-100 mu m size range using divinyl sulfone (DVS) as a crosslinker. The GA microgels were degraded ...
Polyurethane/Tricalcium Phosphate Bone Adhesives and Substitutes for Load Bearing Applications
(Amer Scientific Publishers, 2017)
The large mechanical forces throughout the sternum and upon the tibia, impact healing capacities following sternotomies and upper tibia osteotomies, respectively. In these fields, there remains a need for materials with a ...
Multiwalled Carbon Nanotube-Chitosan Scaffold: Cytotoxic, Apoptotic and Necrotic Effects on Chondrocyte Cell Lines
(Bentham Science Publ Ltd, 2017)
Background: Carbon nanotubes (CNTs) have been considered highly successful and proficient in terms of their mechanical, thermal and electrical functionalization and biocompatibility. In regards to their significant extent ...
Targeted delivery of etoposide to osteosarcoma cells using poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanoparticles
(Tubitak Scientific & Technical Research Council Turkey, 2017)
Folic acid (FA)-functionalized poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanoparticles were prepared to enhance the delivery efficiency of the anticancer drug etoposide for the clinical treatment of osteosarcoma. ...
Synthesis, structural characterization, and cytotoxic activity of new spirocyclic octachlorocyclotetraphosphazenes
(Taylor & Francis Ltd, 2016)
Octachlorocyclotetraphosphazene, N4P4Cl8, (1) was reacted with N, N-dibenzylethylenediamine to synthesize partially substituted monospiro- (2), dispiro- (5) and tetraspirocyclotetraphosphazene (8) derivatives. The reactions ...
Biocompatible and biodegradable poly(Tannic Acid) hydrogel with antimicrobial and antioxidant properties
(Elsevier, 2016)
A novel resourceful bulk poly(Tannic Acid) (p(TA)) hydrogel was prepared by crosslinking TA molecules with an epoxy crosslinker, trimethylolpropane triglycidyl ether (TMPGDE), in an autoclave at 90 degrees C for 2 h. The ...
Modified gold-based siRNA nanotherapeutics for targeted therapy of triple-negative breast cancer
(Future Medicine Ltd, 2017)
Aim: In this study, we aimed to therapeutically target eukaryotic elongation factor 2 kinase (eEF-2K) in an in vivo triple-negative breast cancer (TNBC) tumor model. Materials & methods: We synthesized a highly monodisperse ...
Bi-layered constructs of poly(glycerol-sebacate)-beta-tricalcium phosphate for bone-soft tissue interface applications
(Elsevier Science Bv, 2017)
This study aims to establish a facile protocol for the preparation of a bi-layered poly(glycerol-sebacate) (PGS)/beta-tricalcium phosphate (beta-TCP) construct and to investigate its potential for bone-soft tissue engineering ...
Novel layer-by-layer self-assembled peptide nanocarriers for siRNA delivery
(Royal Soc Chemistry, 2017)
All complex and functional structures of nature consist of simple building blocks that are thermodynamically balanced and self-assembled at the molecular level. Production of functional bio-nanomaterials with molecular ...