Investigation of the Efficacy of Algan Hemostatic Agent in Liver Laceration Model in Rats
Göster/ Aç
Tarih
2019Yazar
Midi, AhmetKumandaş, Ali
Ekici, Hüsamettin
Bayraktar, Feyzanur
Karapirli, Kübra
Karahan, Siyami
Özyürek, H. Emel
Üst veri
Tüm öğe kaydını gösterKünye
Midi, A., Kumandaş, A., Ekici, H., Bayraktar, F., Karapirli, K., Karahan, S., Türk, M., Özyürek, H. E. (2019). Investigation of the Efficacy of Algan Hemostatic Agent in Liver Laceration Model in Rats. Eurasian Journal of Medicine and Oncology, 3(1), 37 - 42.Özet
Objectives: Bleeding control is crucial in preventing negative consequences by reducing blood loss in surgical operations. The aim of this study is to evaluate the hemostatic effect of a new herbal hemostatic agent called Algan Hemostatic Agent (AHA) in an uncontrolled bleeding model made by liver laceration.Methods: In these study 5–7 weeks-old 64 rats were used. Rats were randomly divided into 8 groups each consistingof eight rats (4 groups heparinize and 4 groups non-heparinize). The experimental liver laceration was performed, andphysiological serum impregnated gauze was applied to the control group for hemorrhage control, AHA liquid formimpregnated gauze, AHA gel, and AHA powder form were applied to experimental groups, respectively.Results: The shortest bleeding time was found in the AHA powder group. The AHA powder form stopped the bleedingin the heparinize group for a mean of 4 s, the non-heparinized group for 2 s. This was followed by the gel group and theliquid group. The bleeding time was significantly shorter in the all AHA group compared to the control group.Conclusion: This study showed that AHA is a highly effective hemostatic agent in controlling bleeding compared tothe control group.
Kaynak
Eurasian Journal of Medicine and OncologyCilt
3Sayı
1Bağlantı
https://doi.org/10.14744/ejmo.2018.0008https://app.trdizin.gov.tr/publication/paper/detail/TXpNek5USTVPUT09
https://hdl.handle.net/20.500.12587/1437
Koleksiyonlar
- Makale Koleksiyonu [32]
- Makale Koleksiyonu [96]
- Makale Koleksiyonu [50]
- TR-Dizin İndeksli Yayınlar Koleksiyonu [3218]