Nevus sebaceus: Clinicopathologic features of 17 cases

Abstract

Nevus Sebaceus of Jadassohn is a rare congenital hamartomatous lesion which is usually located on the scalp. Its clinical importance lies mostly in the potential for the development of various secondary neoplasms and its association with 'Nevus sebaceus syndrome'. In this study, we present 17 cases of nevus sebaceus (7,6%) out of 221 cases which were diagnosed as 'Cutaneous adnexal tumor' at the Department of Pathology, Hacettepe University Medical School, between the years 1980-1993. Mean age was 22 years and all lesions were in the head and neck region. Histologic examination of cases were characterized by distribution of three major components; papillomatous hyperplasia, sebaceous glands and apocrine glands. Lost of hair follicles and developmental abnormalities were seen in each case. 3 cases had 5 different secondary neoplasms. The clinical and pathological findings were discussed in the light of literature.