Güncel Gönderiler: Makale Koleksiyonu
Toplam kayıt 48, listelenen: 21-40
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Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury
(Dove Medical Press Ltd, 2016)Background: Ischemia reperfusion injury (I/R) in hind limb is a frequent and important clinical phenomenon. Many structural and functional damages are observed in cells and tissues in these kinds of injuries. In this study, ... -
Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats
(Dove Medical Press Ltd, 2016)Background: Change in blood supply is held responsible for anesthesia-related abnormal tissue and organ perfusion. Decreased erythrocyte deformability and increased aggregation may be detected after surgery performed under ... -
Effects of alprostadil and iloprost on renal, lung, and skeletal muscle injury following hindlimb ischemia-reperfusion injury in rats
(Dove Medical Press Ltd, 2016)Objectives: To evaluate the effects of alprostadil (prostaglandin [PGE1] analog) and iloprost (prostacyclin [PGI2] analog) on renal, lung, and skeletal muscle tissues after ischemia reperfusion (I/R) injury in an experimental ... -
Effects of intravenous ibuprofen and lornoxicam on erythrocyte deformability in rats undergoing hind limb ischemia reperfusion injury
(Comenius Univ, 2016)BACKGROUNDAND AIM: Acute hind limb ischemia reperfusion (I/R) injury is a common consequence of abdominal aorta cross-clamping during aortic surgery. Erythrocyte deformability is affected by I/R process and may lead to ... -
Flufenamic acid prevents behavioral manifestations of salicylate-induced tinnitus in the rat
(Termedia Publishing House Ltd, 2016)Introduction: Tinnitus is defined as a phantom auditory sensation, the perception of sound in the absence of external acoustic stimulation. Given that flufenamic acid (FFA) blocks TRPM2 cation channels, resulting in reduced ... -
Effect of dexmedetomidine on ischemia-reperfusion injury of liver and kidney tissues in experimental diabetes and hepatic ischemia-reperfusion injury induced rats
(Anaesthesia Pain & Intensive Care, 2016)Background: Reperfusion following ischemia can lead to more injuries than ischemia itself especially in diabetic patients. The aim of this study was to evaluate the effect of dexmedetomidine on ischemia-reperfusion injury ... -
Investigation of Effects of Propofol and Vitamin C Administration on Hepatic and Renal Tissue in Diabetic Rats
(Gazi Univ, Fac Med, 2015)Obective: A close relationship between diabetic complications and lipid peroxidation is known. It was shown that in diabetic rat pharmacodynamics and pharmacokinetics of propofol was changed. We aim to investigate effects ... -
Effect of levosimendan on erythrocyte deformability during myocardial ischaemia-reperfusion injury
(Comenius Univ, 2015)Diabetes mellitus (DM) is a chronic metabolic disorder accompanied by an increase in oxidative stress. Ischaemia-reperfusion (IR) injury is a cascade of events initiated by tissue ischaemia. The cellular damage produced ... -
Effect of alprostadil on erythrocyte deformability in ischemia reperfusion injury
(Comenius Univ, 2015)BACKGROUND: Ischemia reperfusion injury (I/R) in lower extremity is a frequent and important clinical phenomenon. Protective effect of alprostadil on local and distant organ injury due to I/R has been well-documented but ... -
The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats
(Comenius Univ, 2015)BACKGROUND: Sugammadex is primarily excreted via renal route. We investigated effects of low and high doses of sugammadex (16 mg/kg versus 96 mg/kg) on renal tissue samples of streptozotocin-induced diabetic rats. MATERIAL ... -
The effects of propofol and memantine on erythrocyte deformability
(Comenius Univ, 2014)Objective: Propofol is an intravenous general anesthetic with a primary hypnotic effect. Memantine is an NMDA receptor antagonist that has been shown to reverse changes in memory and synaptic plasticity in animal models. ... -
The effects of iloprost on lung injury induced by skeletal muscle ischemia-reperfusion
(Comenius Univ, 2014)Purpose: The aim of this study was to investigate the effects of iloprost (I) on lung injury as a remote organ following skeletal muscle ischemia-reperfusion injury in a rat model. Materials and methods: Twenty-four Wistar ... -
Investigation of the effects of propofol and vitamin C administration on erythrocyte deformability in rats with streptozotocin-induced diabetes mellitus
(Comenius Univ, 2014)Purpose: In the current study we aim to investigate the effects of vitamin C and profol on red blood cell deformability in diabetic rats Materials and methods: Twenty- eight Wistar Albino rats were included in the study ... -
The effects of magnesium sulphate on the contractile activity of uterus in an animal model of preeclampsia
(7847050 Canada Inc, 2014)Purpose: This study was undertaken to evaluate the effects of magnesium sulfate (MgSO4) on the contractile activity of the uterus in a pregnant rat model of preeclampsia induced by N-nitro-arginine methyl ester (L-NAME). ... -
Protein Tyrosine Phosphatase Non-receptor 22 Gene C1858T Polymorphism in Patients with Coexistent Type 2 Diabetes and Hashimoto's Thyroiditis
(Galenos Yayincilik, 2014)Background: A protein tyrosine phosphatase non-receptor type 22 (PTPN22) C1858T gene polymorphism has been reported to be associated with both Type 2 diabetes mellitus (T2DM) and Hashimoto's thyroiditis (HT) separately. ... -
Effect of iloprost on erythrocyte deformability in rat's lower extremity undergoing an ischemia reperfusion injury
(Comenius Univ, 2013)Aim: Ischemia reperfusion injury (I/R) in lower extremity is a frequent and important clinical phenomenon. The protective effect of iloprost on local and distant organ injury due to I/R has been well documented but its ... -
Antioxidative effects of adrenomedullin and vascular endothelial growth factor on lung injury induced by skeletal muscle ischemia-reperfusion
(Comenius Univ, 2013)Purpose: The aim of this study was to investigate the effects of adrenomedullin (AM) and vascular endothelial growth factor (VEGF) on lung injury as a remote organ following skeletal muscle ischemia-reperfusion injury in ... -
Does vitamin C prevent the effects of high dose dexmedetomidine on rat erythrocyte deformability?
(Comenius Univ, 2012)Purpose: Dexmedetomidine is an anesthetic agent frequently used for sedation at the intensive care units and during general anesthesia. The purpose of our study was to investigate whether vitamin C prevents the effect of ... -
Dexmedetomidine protects against lipid peroxidation and erythrocyte deformability alterations in experimental hepatic ischemia reperfusion injury
(Taylor & Francis Ltd, 2012)Background: Hepatic ischemia-reperfusion injury is a common clinical problem in hepatic surgery and transplantation. Several cellular and tissue structural and functional alterations are observed in such injury. The aim ... -
The effects of low-high doses of dexmedetomidine on erythrocyte deformability in rats
(Comenius Univ, 2012)Background: Dexmedetomidine is an anesthetic agent frequently used for sedation, intensive care units, and general anesthesia. The purpose of our study was to investigate the effect of two different doses of dexmedetomidine ...