dc.contributor.author | Altintoprak, Niyazi | |
dc.contributor.author | Kar, Murat | |
dc.contributor.author | Muluk, Nuray Bayar | |
dc.contributor.author | Oktemer, Tugba | |
dc.contributor.author | Ipci, Kagan | |
dc.contributor.author | Birdane, Leman | |
dc.contributor.author | Cingi, Cemal | |
dc.date.accessioned | 2020-06-25T18:16:24Z | |
dc.date.available | 2020-06-25T18:16:24Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | closedAccess | en_US |
dc.identifier.issn | 0165-5876 | |
dc.identifier.issn | 1872-8464 | |
dc.identifier.uri | https://doi.org/10.1016/j.ijporl.2016.06.008 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/6516 | |
dc.description | WOS: 000380082000020 | en_US |
dc.description | PubMed: 27368453 | en_US |
dc.description.abstract | We here provide an update on the literature regarding local allergic rhinitis (LAR). In reviewing LAR, we have included an updated definition, classifications, mechanisms, comorbidities, and recommendations for diagnosis and treatment for LAR, as well as the defined research areas for future evidence-based studies. LAR is a localised nasal allergic response in the absence of systemic atopy characterised by local production of specific IgE (sIgE) antibodies, a TH2 pattern of mucosal cell infiltration during natural exposure to aeroallergens, and a positive nasal allergen provocation test response, with the release of inflammatory mediators. The localised allergic response of LAR is an important topic for the study of allergies. This review provides an update on the current knowledge of LAR. (C) 2016 Elsevier Ireland Ltd. All rights reserved. | en_US |
dc.description.sponsorship | Continuing Education and Scientific Research Association | en_US |
dc.description.sponsorship | Preparation of this paper, including design and planning, was supported by the Continuing Education and Scientific Research Association. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier Ireland Ltd | en_US |
dc.relation.isversionof | 10.1016/j.ijporl.2016.06.008 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Local allergic rhinitis | en_US |
dc.subject | Absence | en_US |
dc.subject | Systemic atopy | en_US |
dc.subject | Local production | en_US |
dc.subject | Specific IgE | en_US |
dc.subject | Antibodies | en_US |
dc.subject | Mechanism | en_US |
dc.title | Update on local allergic rhinitis | en_US |
dc.type | review | en_US |
dc.contributor.department | Kırıkkale Üniversitesi | en_US |
dc.identifier.volume | 87 | en_US |
dc.identifier.startpage | 105 | en_US |
dc.identifier.endpage | 109 | en_US |
dc.relation.journal | International Journal Of Pediatric Otorhinolaryngology | en_US |
dc.relation.publicationcategory | Diğer | en_US |