dc.contributor.author | Cakmak, Osman | |
dc.contributor.author | Okten, Salih | |
dc.contributor.author | Alimli, Dilek | |
dc.contributor.author | Saddiqa, Aisha | |
dc.contributor.author | Ersanli, Cem Cuneyt | |
dc.date.accessioned | 2020-06-25T18:29:59Z | |
dc.date.available | 2020-06-25T18:29:59Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1551-7004 | |
dc.identifier.issn | 1551-7012 | |
dc.identifier.uri | https://doi.org/10.24820/ark.5550190.p010.374 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/7523 | |
dc.description | Alimli, Dilek/0000-0003-4564-9447; Hokelek, Tuncer/0000-0002-8602-4382; Okten, Salih/0000-0001-9656-1803 | en_US |
dc.description | WOS: 000438799100030 | en_US |
dc.description.abstract | Quinoline forms the key skeletal component of a number of important natural products and pharmacologically-active compounds. Despite a tremendous amount of research pertaining to the derivatization of quinoline, very few general synthetic routes are described in the literature starting from quinoline or tetrahydroquinoline. A simple and convenient method for the polyfunctionalization of quinolines via nitration of bromoquinolines has been developed. This method represents a new synthetic approach to convert brominated nitroquinoline derivatives into useful cyclic amines via nucleophilic-substitution (SNAr) reaction. [GRAPHICS] . | en_US |
dc.description.sponsorship | Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112T394] | en_US |
dc.description.sponsorship | This study was financially supported by grants from the Scientific and Technological Research Council of Turkey (TUBITAK, Project number: 112T394). The authors thank the Scientific and Technological Research Application and Research Center, Sinop University, Turkey, for the use of the Bruker D8-QUEST diffractometer. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Arkat Usa Inc | en_US |
dc.relation.isversionof | 10.24820/ark.5550190.p010.374 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Nitration | en_US |
dc.subject | N-oxidation | en_US |
dc.subject | 6-bromoquinoline | en_US |
dc.subject | aminoquinoline | en_US |
dc.subject | quinoline N-oxides | en_US |
dc.subject | morpholinyl and piperazinyl quinolines | en_US |
dc.title | Activation of 6-bromoquinoline by nitration: synthesis of morpholinyl and piperazinyl quinolines | en_US |
dc.type | article | en_US |
dc.contributor.department | Kırıkkale Üniversitesi | en_US |
dc.identifier.startpage | 362 | en_US |
dc.identifier.endpage | 374 | en_US |
dc.relation.journal | Arkivoc | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |