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Toplam kayıt 10, listelenen: 1-10
Vitamin C ameliorates high dose Dexmedetomidine induced liver injury
(Comenius Univ, 2016)
BACKGROUND: We investigated whether vitamin C has protective effects on rat liver tissue treated with different dexmedetomidine doses. MATERIAL AND METHODS: Thirty five wistar albino rats were randomly divided into 5 groups ...
Effects of Intracisternal Dexmedetomidine on Cerebral Neuronal Cells in Rat: A Preliminary Study
(Turkish Neurosurgical Soc, 2013)
AIM:The aim was to investigate whether dexmedetomidine had a toxic effect on cerebral neurons when it was administered centrally into the cerebrospinal fluid by the intracisternal route. MATERIAL and METHODS: Eighteen rats ...
The antioxidant effect of dexmedetomidine on testicular ischemia-reperfusion injury
(Acta Cirurgica Brasileira, 2015)
PURPOSE: To investigate the protective effect of dexmedetomidine (Dex) on testicular damage induced by ischemia-reperfusion injury in rats. METHODS: Sham group underwent left scrotal exploration only (group 1). The ...
Dexmedetomidine as an Alternative Anesthetic Agent for Flap Surgery: An Intravital Evaluation in the Cremaster Muscle Flap
(Lippincott Williams & Wilkins, 2019)
Introduction: Flap surgery is one of the most commonly used techniques of reconstructive surgery for effective repair of damaged tissue. Optimal anesthetic technique and anesthetic agent plays an important role in flap ...
Effect of dexmedetomidine on ischemia-reperfusion injury of liver and kidney tissues in experimental diabetes and hepatic ischemia-reperfusion injury induced rats
(Anaesthesia Pain & Intensive Care, 2016)
Background: Reperfusion following ischemia can lead to more injuries than ischemia itself especially in diabetic patients. The aim of this study was to evaluate the effect of dexmedetomidine on ischemia-reperfusion injury ...
The effects of dexmedetomidine on renal injury induced by intra-abdominal hypertension in rats
(Allied Acad, 2016)
Introduction: Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are potentially life-threatening conditions in critically ill patients. Laparascopic surgery is the gold standard and has been widely ...
Protective effects of udenafil citrate, piracetam and dexmedetomidine treatment on testicular torsion/detorsion- induced ischaemia/reperfusion injury in rats
(Wiley-Blackwell, 2016)
The aim of this study was to investigate the antioxidant properties of udenafil citrate (1.4 mg kg(-1)-2.8 mg kg(-1)), dexmedetomidine 25 mu g kg(-1) and piracetam 200 mg kg(-1) administered on ipsilateral/contralateral ...
Effect of Dexmedetomidine on Lung Tissue Lower Extremity Ischemia Reperfusion Injury in Streptozotocin Induced Diabetic Rats
(GAZI UNIV, FAC MED, 2020)
Objective: The aim of our study was to investigate the effects of dexmedetomidine on lung tissue in rat's lower extremity after undergoing an ischemia reperfusion (I/R) injury. Material and methods: After obtaining ethical ...
In Vitro Effect of Dexmedetomidine on Platelet Aggregation
(Elsevier Science Inc, 2013)
Background and objectives: Dexmedetomidine is a selective alpha(2)-agonist. There are 250-300 alpha(2)-agonist-adrenoceptor on the surface of each human platelet and ephedrine induces platelet aggregation by binding these ...
The effects of preanesthetic, single-dose dexmedetomidine on induction, hemodynamic, and cardiovascular parameters
(Elsevier Science Inc, 2008)
Study Objectives: To investigate the hemodynamic, cardiovascular, and recovery effects of dexmedetomidine used as a single preanesthetic dose. Design: Randomized, prospective, double-blind study. Setting: University Hospital ...