Başlık için Biyomühendislik Bölümü listeleme
Toplam kayıt 94, listelenen: 42-61
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Modified gold-based siRNA nanotherapeutics for targeted therapy of triple-negative breast cancer
(Future Medicine Ltd, 2017)Aim: In this study, we aimed to therapeutically target eukaryotic elongation factor 2 kinase (eEF-2K) in an in vivo triple-negative breast cancer (TNBC) tumor model. Materials & methods: We synthesized a highly monodisperse ... -
Multiwalled Carbon Nanotube-Chitosan Scaffold: Cytotoxic, Apoptotic and Necrotic Effects on Chondrocyte Cell Lines
(Bentham Science Publ Ltd, 2017)Background: Carbon nanotubes (CNTs) have been considered highly successful and proficient in terms of their mechanical, thermal and electrical functionalization and biocompatibility. In regards to their significant extent ... -
Nanoemulsions and nonwoven fabrics carrying AgNPs: Antibacterial but may be cytotoxic
(Taylor & Francis Ltd, 2014)The aim of this study is to prepare nonwoven fabrics carrying silver nanoparticles (AgNPs), and to investigate their antibacterial activities and cytotoxicities in parallel. AgNPs were impregnated from their nanoemulsions ... -
Novel fluorescent coumarin-thiophene-derived Schiff bases: Synthesis, effects of substituents, photophysical properties, DFT calculations, and biological activities
(Elsevier Science Sa, 2019)Novel fluorescent coumarin-thiophene appended Schiff bases have been synthesized in good yields (76-89%). The effects of substitution on the fluorescent intensity and solubility of the molecules were examined with experimental ... -
Novel layer-by-layer self-assembled peptide nanocarriers for siRNA delivery
(Royal Soc Chemistry, 2017)All complex and functional structures of nature consist of simple building blocks that are thermodynamically balanced and self-assembled at the molecular level. Production of functional bio-nanomaterials with molecular ... -
Novel Phthalocyanines Containing Guaiacol Azo Dyes: Synhthesis, Antioxidant, Antibacterial, and Anticancer Activity
(Pleiades Publishing Inc, 2018)In an attempt to understand the antibacterial, antioxidant, and anticancer properties of phthalocyanines containing azo dye, new metallophthalocyanines (M: Mn, Co, Zn) substituted with guaiacol azo dyes are described. The ... -
Novel phthalocyanines containing resorcinol azo dyes; synthesis, determination of pKa values, antioxidant, antibacterial and anticancer activity
(Elsevier Science Sa, 2015)There are many studies about effects on health of compounds having azo groups in literature. However, anticancer, antimicrobial and antioxidant properties of phthalocyanines containing azo dyes are unknown. Therefore, the ... -
One-pot facile synthesis of silk sericin-capped gold nanoparticles by UVC radiation: Investigation of stability, biocompatibility, and antibacterial activity
(Wiley, 2019)Herein, an easy one-pot synthesis method for gold nanoparticles (AuNPs), involving only gold salt and sericin extracted from silkworm cocoon in the presence of ultraviolet C (UVC) radiation, was developed. Nanoparticle ... -
Pectin-conjugated magnetic graphene oxide nanohybrid as a novel drug carrier for paclitaxel delivery
(Taylor & Francis Ltd, 2018)Recent studies have shown that graphene oxide (GO) drug carrier functionalized with biocompatible natural polymers lead to higher loading efficacy and better stability with diminished cellular toxicity. Pectin (PEC) is one ... -
Periodic monitoring of persistent organic pollutants and molecular damage in Cyprinus carpio from Buyuk Menderes River
(Springer Heidelberg, 2017)Concentrations of persistent organic pollutants (POPs) were quantified in river water and sediment, as well as in the liver and muscle tissues of Cyprinus carpio that were sampled four times in a year at three stations in ... -
Phosphorus nitrogen compounds: Part 34. Syntheses, structural investigations, cytotoxic and biological activities of spiro-ansa-spiro and spiro-bino-spiro tetrameric phosphazene derivatives
(Elsevier Science Sa, 2016)The reactions of N4P4Cl8 with the symmetric N2N2 (1-3) and N2O2 (4) bulky ligands gave partly substituted 2,4-sas (5 and 6), 2,6-sas (7-10) and sbs (11-14) tetrameric phosphazene derivatives. The 2,4-sas-5, 2,6-sas-8 and ... -
Phosphorus-nitrogen compounds Part 32. Structural and thermal characterizations, antimicrobial and cytotoxic activities, and in vitro DNA binding of the phosphazenium salts
(Springer, 2016)The salicylic acid salts of fully substituted mono(4-fluorobenzyl)spirocyclotriphosphazenes (10-15) were prepared. The structures of these phosphazenium salts (10a-15a) were determined by elemental analyses, FTIR and H-1, ... -
Phosphorus-nitrogen compounds part 33: in vitro cytotoxic and antimicrobial activities, DNA interactions, syntheses, and structural investigations of new mono(4-nitrobenzyl)spirocyclotriphosphazenes
(Springer, 2016)The condensation reactions of hexachlorocyclotriphosphazene, N3P3Cl6, with N-alkyl-N'-mono(4-nitrobenzyl)diamines (1-3), NO2PhCH2NH(CH2) (n) NHR1 (R-1 = CH3 or C2H5), led to the formation of the mono(4-nitrobenzyl)spiroc ... -
Phosphorus-nitrogen compounds. Part 35. Syntheses, spectroscopic and electrochemical properties, and antituberculosis, antimicrobial and cytotoxic activities of mono-ferrocenyl-spirocyclotetraphosphazenes
(Royal Soc Chemistry, 2016)The reactions of octachlorocyclotetraphosphazene, N4P4Cl8, with N-alkyl-N-mono-ferrocenyldiamines, FcCH(2)NH(CH2)(n)NHR1 [n = 2, Fc = ferrocene, R-1 = Me (1); n = 2, R-1 = Et (2) and n = 3, R-1 = Me (3)], led to the formation ... -
Phosphorus-nitrogen compounds. Part 36. Syntheses, Langmuir-Blodgett thin films and biological activities of spiro-bino-spiro trimeric phosphazenes
(Royal Soc Chemistry, 2016)The condensation reactions of hexachlorocyclotriphosphazene (N3P3Cl6, trimer) with the symmetric N2N2 or N2O2 donor type tetradentate bulky ligands (1-4) gave partly substituted spiro-bino-spiro (sbs) (5-8) trimeric ... -
Phosphorus-nitrogen compounds. Part 37. Syntheses and structural characterizations, biological activities of mono and bis(4-fluorobenzyl)spirocyclotetraphosphazenes
(Royal Soc Chemistry, 2017)The Cl substitution reactions of octachlorocyclotetraphosphazene, N4P4Cl8, with one equimolar amount of (4-fluorobenzyl)diamines (1-3) affords mono(4-fluorobenzyl) spirocyclotetraphosphazenes (4-6) as minor products. ... -
Phosphorus-nitrogen compounds. part 38. Syntheses, characterizations, cytotoxic, antituberculosis and antimicrobial activities and DNA interactions of spirocyclotetraphosphazenes with bis-ferrocenyl pendant arms
(Elsevier Science Sa, 2017)The reactions of N4P4Cl8 (1), with two equimolar amounts of N-(1-ferrocenylmethyl)-N-methyl-propylenediamine gave the monoferrocenyl-spiro (as a byproduct), bisferrocenyl-2-trans-6-dispiro (2) and bisferrocenyl-2-cis-6-dispiro ... -
Phosphorus-nitrogen compounds. Part 42. The comparative syntheses of 2-cis-4-ansa(N/O) and spiro(N/O) cyclotetraphosphazene derivatives: spectroscopic and crystallographic characterization, antituberculosis and cytotoxic activity studies
(Royal Soc Chemistry, 2019)The reaction of N4P4Cl8 (1) with one equimolar amount of the sodium salt of an N/O donor-type bidentate ligand (2) afforded two kinds of derivatives, namely, mono-ferrocenyl-2-cis-4-dichloro-ansa- (2,4-ansa; 3) and ... -
Phosphorus-nitrogen compounds. Part 44. The syntheses of N,N-spiro bridged cyclotriphosphazene derivatives with (4-fluorobenzyl) pendant arms: Structural and stereogenic properties, DNA interactions, antimicrobial and cytotoxic activities
(Elsevier Science Sa, 2019)Isopropylaminopentachlorocyclotriphosphazene, (N3P3Cl5(NHCHMe2) (1), containing a P-NH group in the alkyl-chain, gives the NN-spirobridged octachlorobiscyclotriphosphazene, [N3P3Cl4(NCHMe2)](2) (2), in the presence of NaH. ... -
Phosphorus-nitrogen compounds. Part 48. syntheses of the phosphazenium salts containing 2-pyridyl pendant arm: structural characterizations, thermal analysis, antimicrobial and cytotoxic activity studies
(NATL INST SCIENCE COMMUNICATION-NISCAIR, 2020)The phosphazenium salts (protic ionic liquids, PILs/protic molten salts, PMOSs) (6a-6d and 7a) of the free phosphazene bases (4a-4d and 5a) have been prepared by the reactions of the corresponding cyclotriphosphazenes with ...