Ara
Toplam kayıt 66, listelenen: 11-20
Modified gold-based siRNA nanotherapeutics for targeted therapy of triple-negative breast cancer
(Future Medicine Ltd, 2017)
Aim: In this study, we aimed to therapeutically target eukaryotic elongation factor 2 kinase (eEF-2K) in an in vivo triple-negative breast cancer (TNBC) tumor model. Materials & methods: We synthesized a highly monodisperse ...
Phosphorus-nitrogen compounds. Part 37. Syntheses and structural characterizations, biological activities of mono and bis(4-fluorobenzyl)spirocyclotetraphosphazenes
(Royal Soc Chemistry, 2017)
The Cl substitution reactions of octachlorocyclotetraphosphazene, N4P4Cl8, with one equimolar amount of (4-fluorobenzyl)diamines (1-3) affords mono(4-fluorobenzyl) spirocyclotetraphosphazenes (4-6) as minor products. ...
Bi-layered constructs of poly(glycerol-sebacate)-beta-tricalcium phosphate for bone-soft tissue interface applications
(Elsevier Science Bv, 2017)
This study aims to establish a facile protocol for the preparation of a bi-layered poly(glycerol-sebacate) (PGS)/beta-tricalcium phosphate (beta-TCP) construct and to investigate its potential for bone-soft tissue engineering ...
Novel phthalocyanines containing resorcinol azo dyes; synthesis, determination of pKa values, antioxidant, antibacterial and anticancer activity
(Elsevier Science Sa, 2015)
There are many studies about effects on health of compounds having azo groups in literature. However, anticancer, antimicrobial and antioxidant properties of phthalocyanines containing azo dyes are unknown. Therefore, the ...
Phosphorus-nitrogen compounds: Part 31. Syntheses, structural and stereogenic properties, in vitro cytotoxic and antimicrobial activities, and DNA interactions of bicyclotetraphosphazenes containing bulky side group
(Elsevier Science Sa, 2015)
Hexachlorocyclotriphosphazene, N3P3Cl6, and octachlorocyclotetraphosphazene, N4P4Cl8, were reacted with K2N2O2 salt of symmetric tetradentate ligand to obtain spiro-bino-spiro [(sbs) (2)] and 2,6-spiro-ansa-spiro [(2,6-sas) ...
Removal of various anionic dyes using sodium alginate/poly(N-vinyl-2-pyrrolidone) blend hydrogel beads
(Springer, 2015)
In this study, novel blend hydrogel beads were prepared for the use in removal of anionic textile dyes due to their hazardous impact to nature. Sodium alginate and sodium alginate/poly(N-vinyl-2-pyrrolidone) beads were ...
Downregulation of ABCE1 via siRNA affects the sensitivity of A549 cells against chemotherapeutic agents
(Humana Press Inc, 2015)
ATP-binding cassette E1 (ABCE1) is involved in several biological functions in cancer cells such as tumor proliferation, antiapoptotic pathway and chemoresistance mechanism. This work aimed to investigate the alterations ...
Aptamer-functionalized magnetic graphene oxide nanocarrier for targeted drug delivery of paclitaxel
(Elsevier Science Sa, 2018)
Targeted drug delivery has come out as a golden system owing to its capability to reduce side effects and increase efficacy. The application of graphene oxide (GO) based nanomaterials for targeted delivery has recently ...
Syntheses, spectroscopic and crystallographic characterizations of cis- and trans-dispirocyclic ferrocenylphosphazenes: molecular dockings, cytotoxic and antimicrobial activities
(Royal Soc Chemistry, 2018)
New cis-(4-6) and trans-dispirocyclic ferrocenylphosphazene derivatives (7-9) were obtained by reactions of hexachlorocyclotriphosphazene (N3P3Cl6) with N-alkyl-N-monoferrocenyldiamines of the formula FcCH(2)NH(CH2)(n)NHR ...
Synthesis and biological activity of ferrocenyl furoyl derivatives
(Taylor & Francis Inc, 2017)
Due to the fact that ferrocene and furan derivatives have long been known to be one of the most biologically active compounds, preparation of their new derivatives might serve a very important purpose. Herein, five furoyl ...