Güncel Gönderiler: Makale Koleksiyonu
Toplam kayıt 72, listelenen: 21-40
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Focusing-free impedimetric differentiation of red blood cells and leukemia cells: A system optimization
(ELSEVIER SCIENCE SA, 2020)A focusing-free microfluidic impedimetric cell detection system is developed. The effect of the channel dimensions, solution conductivity, excitation voltage, and particle size on impedimetric signal outputs were optimized ... -
Decision making for promising quinoline-based anticancer agents through combined methodology
(WILEY, 2020)During the development of effective drugs for the treatment of cancer, one of the most important tasks is to identify effective drug candidates having maximum antiproliferation and minimum side effects. This paper considers ... -
The Effect of REACT and Computer-Assisted Instruction Model in 5E on Student Achievement of the Subject of Acids, Bases and Salts
(SPRINGER, 2020)This research was carried out to investigate the effect of the 5E learning method and 5E method enriched with REACT strategy on student achievement in science education. The research was carried out with 64 first-year ... -
The investigation of the healing effect of active ingredients in traditional medicinal plants on lung cancer
(HUMANA PRESS INC, 2020)The healing effect of herbal active compounds on lung cancer has been recently investigated. Lung cancer is one of the leading types of cancer. The causes and prevention of lung cancer diagnosis have an important role as ... -
Novel piperazine and morpholine substituted quinolines: Selective synthesis through activation of 3,6,8-tribromoquinoline, characterization and their some metabolic enzymes inhibition potentials
(ELSEVIER, 2020)Regioselective routes are described for convenient preparation of novel piperazine/morpholine substituted quinoline derivatives at C-3, C-6 and C-8 starting with 3,6,8-tribromoquinoline (6) by nucleophilic substitution via ... -
The adaptation of the pedagogical knowledge and skills survey into Turkish: Validity and reliability study
(Mehmet Tekerek, 2019)This research aims to adapt the Pedagogical Knowledge and Skills in Teaching (PKST) survey developed by Wong, Chong, Choy and Lim (2012) to Turkish. The participants of the study are 830 4th year students of education ... -
Synthesis, characterization, crystal structures, theoretical calculations and biological evaluations of novel substituted tacrine derivatives as cholinesterase and carbonic anhydrase enzymes inhibitors
(Elsevier Science Bv, 2019)The six and seven hydrocycle membered disilylanilino acridine (tacrine) analogues (9-11) were synthesized by one-pot procedures. The structures of novel silyl tacrine derivatives were characterized by NMR spectroscopy, ... -
Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties
(Wiley-V C H Verlag Gmbh, 2019)The synthesis, characterization, aggregation behavior, theoretical studies, and investigation of antimicrobial, antidiabetic, and anticholinergic properties of 4-(2-(5-amino-4-(4-bromophenyl)-3-methyl-1H-pyrazol-1-yl)eth ... -
SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors
(Assoc Pharmaceutical Teachers India, 2019)Background: The inhibition of both hydrolysis products of acetylcholine (ACh), Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), is essential for successful treatment of Alzhemier patients. Objectives: This ... -
An investigation of the olive phenols activity as a natural medicine
(Food & Drug Adminstration, 2018)The natural antioxidants of olive oil have phenolic structure and their activities are related to the formation of stable derivatives. In this study, the single components of the phenolic fraction of olive oil (1,4-hydroquinone, ... -
Synthesis, characterization, and SAR of arylated indenoquinoline-based cholinesterase and carbonic anhydrase inhibitors
(Wiley-V C H Verlag Gmbh, 2018)We report the synthesis of bromoindenoquinolines (15a-f) by Friedlander reactions in low yields (13-50%) and the conversion of the corresponding phenyl-substituted indenoquinoline derivatives 16-21 in high yields (80-96%) ... -
The inhibition effect of garlic-derived compounds on human immunodeficiency virus type 1 and saquinavir
(Wiley, 2018)Garlic has been used as a traditional medicine to treat various diseases. Garlic reduces the risk of some diseases. This protective effect is due to the organosulfur compounds of garlic. The aim of this study was to ... -
Theoretical Study of Synthesis of 1,3-dibromonaphthanlene
(Chem Soc Pakistan, 2018)Naphthalene derivatives have been attracted the interest for synthesis of natural products having biological properties. Elimination reaction of tetrabromonaphthalene (1) resulted in the formation of 1,3-dibromonaphthalene ... -
A SAR Study: Evaluation of Bromo Derivatives of 8-Substituted Quinolines as Novel Anticancer Agents
(Bentham Science Publ Ltd, 2017)Background: Brominated 8-hydroxy, 8-methoxy, 8-amino quinolines 5, 6, 8, 9 and novel cyano 8-hydroxyquinolines 11, 12 were evaluated in vitro for their anticancer effects on various cell lines. 5,7-Dibromo-5, 7-bromo-6, ... -
A New Approach Of Gluten Derivatives For Activity As Theoretical
(Yildiz Technical Univ, 2017)Gluten is the mainly rubbery mass that remains after wheat dough is being washed to remove starch granules and water-soluble constituents. Gluten is known as proteins and it plays an important role in indicating the unique ... -
A Study On The Chemical Properties Of Eugenol And Eugenol Acetate, Clove Essential Oils
(Yildiz Technical Univ, 2016)Eugenol and eugenol acetate are a clove essential oil getting from hydrodistilltion of Syzygium aromaticum's buds and leaves. It has antimicrobial, antioxidant, analgesic, anticancer activities and used for protecting foods ... -
An Examination of Cross Sectional Change in Student's Metaphorical Perceptions towards Heat, Temperature and Energy Concepts
(Necmettin Erbakan Univ, 2016)In science teaching, metaphors are important tools for understanding meaningful learning and conceptual formation by the help of daily life language. This study aims to evaluate how the concepts of heat, temperature and ... -
Augmented reality in science laboratories: The effects of augmented reality on university students' laboratory skills and attitudes toward science laboratories
(Pergamon-Elsevier Science Ltd, 2016)This study investigated the effects of the use of augmented reality (AR) technologies in science laboratories on university students' laboratory skills and attitudes towards laboratories. A quasi-experimental pre-test/post-test ... -
Effect of heat treatment on the microstructures and mechanical properties of Al-5.5Zn-2.5Mg alloy
(Elsevier Science Sa, 2016)The Al-5.5 Zn-2.5 Mg (wt%) ternary alloy was prepared using a vacuum melting furnace and a casting furnace. Microstructural and mechanical properties of the alloy were investigated as-cast and under heat-treated conditions. ... -
Convenient synthesis of disubstituted tacrine derivatives via electrophilic and copper induced reactions
(Pergamon-Elsevier Science Ltd, 2016)The bromination of 2-aminobenzonitrile (2) with molecular bromine (2 equiv) furnished 2-amino-3,5-dibromobenzonitrile (7) in 98% yield. One-pot syntheses are described for dibromotacrine derivatives (6,14-18) utilizing ...