Yazar "Comu, Faruk Metin" için listeleme
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Dexmedetomidine protects against lipid peroxidation and erythrocyte deformability alterations in experimental hepatic ischemia reperfusion injury
Arslan, Mustafa; Comu, Faruk Metin; Kucuk, Aysegul; Ozturk, Levent; Yaylak, Faik (Taylor & Francis Ltd, 2012)Background: Hepatic ischemia-reperfusion injury is a common clinical problem in hepatic surgery and transplantation. Several cellular and tissue structural and functional alterations are observed in such injury. The aim ... -
Effect of dexmedetomidine on ischemia-reperfusion injury of liver and kidney tissues in experimental diabetes and hepatic ischemia-reperfusion injury induced rats
Sezen, Saban Cem; Isik, Berrin; Bilge, Mustafa; Arslan, Mustafa; Comu, Faruk Metin; Ozturk, Levent; Kavutcu, Mustafa (Anaesthesia Pain & Intensive Care, 2016)Background: Reperfusion following ischemia can lead to more injuries than ischemia itself especially in diabetic patients. The aim of this study was to evaluate the effect of dexmedetomidine on ischemia-reperfusion injury ... -
The effect of dexmedetomidine on myocardial ischemia reperfusion injury in streptozotocin induced diabetic rats
Arslan, Mustafa; Poyraz, Fatih; Kiraz, Hasan Ali; Alkan, Metin; Kip, Gulay; Erdem, Ozlem; Comu, Faruk Metin (Anaesthesia Pain & Intensive Care, 2015)Objective: Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio-protective ... -
Effect of different doses of pregabalin on erythrocyte deformability in rats with lower limb ischemia reperfusion injury
Ozer, Abdullah; Comu, Faruk Metin; Demirtas, Huseyin; Kilic, Yigit; Mardin, Baris; Ozturk, Levent; Kucuk, Aysegul (Anaesthesia Pain & Intensive Care, 2017)Background & Objective: Acute ischemia reperfusion (IR) injury observed in the lower extremities occurs especially when a temporary cross-clamp is applied to the abdominal aorta during aortic surgery. Preoperative pregabalin ... -
The effect of different types of honey on healing infected wounds
Eroglu, Oguz; Deniz, Turgut; Kisa, Ucler; Comu, Faruk Metin; Kaygusuz, Sedat; Kocak, Orhan Murat (Ma Healthcare Ltd, 2018)Objective: To investigate the effects of treatments of 'mad honey', blossom honey and nitrofurazone on infected wound healing. Method: Male albino Wistar rats were randomly divided into four groups: 'mad honey' (MH), blossom ... -
Effect of Fullerenol C60 on Erythrocyte Deformability During Ischaemia-Reperfusion Injury of Lower Extremity in Diabetic Rats
Kip, Gulay; Kartal, Hakan; Comu, Faruk Metin; Polat, Yucel; Arslan, Mustafa; Kucuk, Aysegul (Gazi Univ, Fac Med, 2019)Background: Fullerenol, a water-soluble C60-fullerene derivative synthesized by Chiang et al, has been demonstrated to be able to scavenge free radicals in vitro and in vivo. Although its protective effects have been already ... -
The effect of levosinnendan on myocardial ischemia reperfusion injury in streptozotocin-induced diabetic rats
Kiraz, Hasan Ali; Poyraz, Fatih; Kip, Gulay; Erdem, Ozlem; Alkan, Metin; Arslan, Mustafa; Comu, Faruk Metin (Co-Action Publishing, 2015)Objective: Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio ... -
Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury
Comu, Faruk Metin; Kilic, Yigit; Ozer, Abdullah; Kirisci, Mehmet; Dursun, Ali Dogan; Tatar, Tolga; Arslan, Mustafa (Dove Medical Press Ltd, 2016)Background: Ischemia reperfusion injury (I/R) in hind limb is a frequent and important clinical phenomenon. Many structural and functional damages are observed in cells and tissues in these kinds of injuries. In this study, ... -
The Effect of Picroside-2 on Erythrocyte Deformability and Lipid Peroxidation in Streptozotocin-Induced Diabetic Rats subjected to Left Anterior Descending Artery-Ischemia reperfusion (conferenceObject)
Comu, Faruk Metin; Polat, Yucel; Ozer, Abdullah; Erer, Dilek; Kirisci, Mehmet; Dursun, Ali Dogan; Arslan, Mustafa (Wiley-Blackwell, 2015)… -
Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats
Arpaci, Hande; Comu, Faruk Metin; Kucuk, Aysegul; Kosem, Bahadir; Kartal, Seyfi; Sivgin, Volkan; Arslan, Mustafa (Dove Medical Press Ltd, 2016)Background: Change in blood supply is held responsible for anesthesia-related abnormal tissue and organ perfusion. Decreased erythrocyte deformability and increased aggregation may be detected after surgery performed under ... -
The Effects of Simvastatin on Ischemia Reperfusion Injury in an Experimental Colon Anastomosis Model
Akarsu, Mahmut; Saygun, Oral; Aydinuraz, Kuzey; Aydin, Oktay; Daphan, Cagatay Erden; Tanrikulu, Fatma Benli; Comu, Faruk Metin (Springer India, 2017)Anastomotic leakage is more frequently reported in colonic anastomoses. Ischemia reperfusion injury is one of the main reasons for anastomotic leakage. Simvastatin is known to prevent tissue damage induced by free oxygen ... -
Effects of the general anaesthetic agent, propofol, on erythrocyte deformability
Arslan, Mustafa; Comu, Faruk Metin; Isik, Berrin; Unal, Yusuf; Cekmen, Nedim; Kurtipek, Omer (Comenius Univ, 2010)Objectives: Propofol is an anesthetic agent frequently used for sedation and general anesthesia. The purpose of our study was to investigate the effect of propofol, a general anesthetic, on erythrocyte deformability in ... -
Evaluation of Erythrocyte Deformability in Experimentally Induced Osteoporosis in Male Rats and the Effects of Vitamin C Supplementation on Erythrocyte Deformability and Bone Mineral Density
Arslan, Mustafa; Comu, Faruk Metin; Keles, Isik; Arslan, Ayse (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2012)Objective: Male osteoporosis (OP) is a major problem in clinical medicine, but has gained less interest than female OP The mechanisms of male OP have not been explained well and are not clear yet. It is suggested that there ...