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Toplam kayıt 36, listelenen: 1-10
Preparation and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHX) based nanoparticles for targeted cancer therapy
(Elsevier Science Bv, 2011)
Targeted drug delivery systems are one of the most promising alternatives for the cancer therapy. Rapid developments on nanomedicine facilitated the creation of novel nanotherapeutics by using different nanomaterials. ...
Potential c-myc Antisense Oligonucleotide Carriers: PCl/PEG/PEI and PLL/PEG/PEI
(Informa Healthcare, 2011)
In this work, positively charged, micelle-forming polymers were synthesized and used as a model vector to deliver antisense oligodeoxynucleotide (ASODN) into melanoma cells. Polymers and polymer/ASODN complexes were ...
Novel phthalocyanines containing resorcinol azo dyes; synthesis, determination of pKa values, antioxidant, antibacterial and anticancer activity
(Elsevier Science Sa, 2015)
There are many studies about effects on health of compounds having azo groups in literature. However, anticancer, antimicrobial and antioxidant properties of phthalocyanines containing azo dyes are unknown. Therefore, the ...
Downregulation of ABCE1 via siRNA affects the sensitivity of A549 cells against chemotherapeutic agents
(Humana Press Inc, 2015)
ATP-binding cassette E1 (ABCE1) is involved in several biological functions in cancer cells such as tumor proliferation, antiapoptotic pathway and chemoresistance mechanism. This work aimed to investigate the alterations ...
Phosphorus-nitrogen compounds: Part 31. Syntheses, structural and stereogenic properties, in vitro cytotoxic and antimicrobial activities, and DNA interactions of bicyclotetraphosphazenes containing bulky side group
(Elsevier Science Sa, 2015)
Hexachlorocyclotriphosphazene, N3P3Cl6, and octachlorocyclotetraphosphazene, N4P4Cl8, were reacted with K2N2O2 salt of symmetric tetradentate ligand to obtain spiro-bino-spiro [(sbs) (2)] and 2,6-spiro-ansa-spiro [(2,6-sas) ...
Antisense oligonucleotide delivery to cancer cell lines for the treatment of different cancer types
(Taylor & Francis Ltd, 2016)
Amphiphilic poly(3-hydroxylalkanoate) (PHA) copolymers find interesting applications in drug delivery. The aim of this study was to prepare nucleic acid adsorbed on (PHB-b-PEG-NH2) nanoparticle platform for gene delivery. ...
Calcified and mechanically debilitated three-dimensional hydrogel environment induces hypertrophic trend in chondrocytes
(Sage Publications Ltd, 2016)
Currently, the main focus on tissue engineering strategies is to mimic the extracellular matrix of the related tissues. Many studies accomplished to build tissue scaffolds to act as the natural surroundings of the specific ...
Multiwalled Carbon Nanotube-Chitosan Scaffold: Cytotoxic, Apoptotic and Necrotic Effects on Chondrocyte Cell Lines
(Bentham Science Publ Ltd, 2017)
Background: Carbon nanotubes (CNTs) have been considered highly successful and proficient in terms of their mechanical, thermal and electrical functionalization and biocompatibility. In regards to their significant extent ...
Synthesis, characterization and modification of Gum Arabic microgels for hemocompatibility and antimicrobial studies
(Elsevier Sci Ltd, 2017)
Gum Arabic (GA) microgels were successfully prepared via reverse micellization method with high yield (78.5 +/- 5.0%) in 5-100 mu m size range using divinyl sulfone (DVS) as a crosslinker. The GA microgels were degraded ...
Polyurethane-Ceramic matrices as orbital implants
(Taylor & Francis As, 2018)
Orbital implants are used in such procedures as a method by which the natural void created by the removal of an eye can be filled to restore structural and mechanical stability in the region. Highly biocompatible, ...