Changes in cerebral and ocular hemodynamics in Behget's disease assessed by color-coded duplex sonography
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closedAccessAbstract
Aim: To quantify the cerebral and retrobulbar hemodynamics in Behqet's disease with and without ocular involvement and compared with that of healthy controls. Materials and methods: Of 5 1 people studied, 17 had Behqet's disease with ocular involvement, 17 had Behqet's disease without ocular involvement, and 17 were healthy controls. A single eye was examined in each patient. Peak systolic velocity (PSV), end-diastolic velocity (EDV), time-averaged maximum velocity (Tamax), and resistance index (RI) were evaluated in the ophthalmic (OA), posterior ciliary (PCA), central retinal (CRA) and middle cerebral artery (MCA). Additionally, the average blood flow velocities in the central retinal vein (CRV), and acceleration time (AT) and pulsatility index (PI) in the MCA were calculated. Results: The mean EDV in the PCA was 25% lower and RI was higher in patients with ocular involvement of BD than in patients without involvement (p = 0.006 and p = 0.005, respectively) and in healthy controls (p = 0.003 and p = 0.004, respectively). Differences were smaller in comparisons of the CRA and absent on comparisons of the OA and MCA. The acceleration time of the MCA was significantly higher in patients with Behqet's disease than in healthy controls (p = 0.03). Conclusion: This study suggests that the flow hemodynamics in retrobulbar circulation has more altered Behcet's disease with ocular involvement than without ocular involvement and healthy control. Additionally, the cerebral hemodynamic might be affected in patients with Behqet's disease compared with healthy controls. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
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European Journal Of RadiologyVolume
58Issue
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