Non-Acidic Mediated Friedel-Craft Reaction of Thiophene Using EtAlCl2
Citation
Unver, H., Biyikoglu, M., & Bulut, A. (2013). Non-Acidic Mediated Friedel-Craft Reaction of Thiophene Using EtAlCl2. Asian Journal of Chemistry, 25(15), 8772–8774.Abstract
Since alkyl Lewis acids are Bronsted bases, they give a non-acidic reaction media. In this context, acylation of thiophene is investigated in the presence of EtAlCl2 and non-acidic media. Besides 8 examples of thiophene, one example for pyrrole is synthesized in moderate to high yields (up to 99 %).
Source
Asian Journal Of ChemistryVolume
25Issue
15Collections
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