dc.contributor.author | Onaran, Zafer | |
dc.contributor.author | Konuk, Onur | |
dc.contributor.author | Oktar, Suna Ozhan | |
dc.contributor.author | Yucel, Cem | |
dc.contributor.author | Unal, Mehmet | |
dc.date.accessioned | 2020-06-25T18:12:11Z | |
dc.date.available | 2020-06-25T18:12:11Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | closedAccess | en_US |
dc.identifier.issn | 0271-3683 | |
dc.identifier.issn | 1460-2202 | |
dc.identifier.uri | https://doi.org/10.3109/02713683.2013.867355 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/5790 | |
dc.description | WOS: 000336995500003 | en_US |
dc.description | PubMed: 24502333 | en_US |
dc.description.abstract | Purpose: To investigate the effects of combined orbital bone and fat decompression on intraocular pressure (IOP) and superior ophthalmic vein blood flow velocity (SOV-BFV), and their association with the clinical features of Graves orbitopathy (GO). Methods: During the 2002-2008 period, 72 eyes of 36 GO cases demonstrating moderate to severe orbitopathy were evaluated according to their clinical features as: cases with or without dysthyroid optic neuropathy (DON), and underwent orbital decompression. A control group comprised 40 eyes of 20 healthy subjects. In both groups, a full ophthalmic examination including IOP and Hertel measurements was performed, and SOV-BFV was analyzed with color Doppler imaging. Examinations were repeated after orbital decompression in GO patients. Results: All the cases demonstrated clinical features of inactive disease. Among the patients 24 of 72 eyes (33.3%) showed clinical features of DON. After surgery, the mean decrease in Hertel values was 6.2 +/- 1.8mm (p = 0.001). The mean decrease in IOP was 3.0 +/- 1.7mmHg (from 17.3 +/- 2.7 to 14.3 +/- 2.0mmHg) after orbital decompression where the post-operative values were comparable with the control group (12.9 +/- 1.4mmHg, p = 0.36). The mean increase in SOV-BFV achieved with decompression was 1.2 +/- 0.6 cm/s (from 4.8 +/- 1.7 to 6.0 +/- 1.8 cm/s) and post-operative SOV-BFV values were also comparable with the control group (6.6 +/- 1.3 cm/s, p = 0.26). The increase in SOV-BFV in cases with DON did not differ from cases without DON (p = 0.32), however, post-operative SOV-BFV of cases with DON was stil lower than cases without DON (p = 0.035). Conclusions: Combined orbital bone and fat decompression significantly reduced the IOP levels and increased the SOV-BFV in GO. This could be the confirmative finding of prediction that elevated IOP in GO is associated with increased episcleral venous pressure. The post-operative changes in IOP and SOV-BFV show differences regarding the clinical features of disease. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Informa Healthcare | en_US |
dc.relation.isversionof | 10.3109/02713683.2013.867355 | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Dysthyroid optic neuropathy | en_US |
dc.subject | Graves orbitopathy | en_US |
dc.subject | intraocular pressure | en_US |
dc.subject | orbital decompression | en_US |
dc.subject | superior ophthalmic vein | en_US |
dc.title | Intraocular Pressure Lowering Effect of Orbital Decompression is Related to Increased Venous Outflow in Graves Orbitopathy | en_US |
dc.type | article | en_US |
dc.contributor.department | Kırıkkale Üniversitesi | en_US |
dc.identifier.volume | 39 | en_US |
dc.identifier.issue | 7 | en_US |
dc.identifier.startpage | 666 | en_US |
dc.identifier.endpage | 672 | en_US |
dc.relation.journal | Current Eye Research | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |