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dc.contributor.authorAydin, H. M.
dc.contributor.authorSalimi, K.
dc.contributor.authorYilmaz, M.
dc.contributor.authorTurk, M.
dc.contributor.authorRzayev, Z. M. O.
dc.contributor.authorPiskin, E.
dc.date.accessioned2020-06-25T18:22:33Z
dc.date.available2020-06-25T18:22:33Z
dc.date.issued2016
dc.identifier.citationclosedAccessen_US
dc.identifier.issn1932-6254
dc.identifier.issn1932-7005
dc.identifier.urihttps://doi.org/10.1002/term.1759
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6794
dc.descriptionBayram, Cem/0000-0001-8717-4668; yilmaz, mehmet/0000-0003-2687-9167; yilmaz, mehmet/0000-0003-2687-9167en_US
dc.descriptionWOS: 000368577300004en_US
dc.descriptionPubMed: 23671061en_US
dc.description.abstractIn this study, poly(glycerol-co-sebacate-co-epsilon-caprolactone) (PGSCL) elastomers were synthesized for the first time from the respective monomers. The structural analysis of PGSCL elastomers by nuclear magnetic resonance (H-1-NMR) and Fourier transform infrared spectroscopy (FTIR) revealed that the elastomers have a high number of hydrogen bonds and crosslinks. X-ray diffraction (XRD) and thermal analysis indicated an amorphous state. Differential scanning calorimetry (DSC) analysis showed that the elastomers has a glass transition temperature (T-g) of -36.96 degrees C. The Young's modulus and compression strength values were calculated as 46.08MPa and 3.192MPa, respectively. Calculations based on acid number and end groups analysis revealed a number average molecular weight of 148.15kDa. Even though the foaming studies conducted by using supercritical CO2 resulted in a porous structure; the obtained morphology tended to disappear after 48h, leaving small cracks on the surface. This phenomenon was interpreted as an indication of self-healing due to the high number of hydrogen bonds. The PGSCL elastomers synthesized in this study are flexible, robust to compression forces and have self-healing capacity. Thanks to good biocompatibility and poor cell-adhesion properties, the elastomers may find diverse applications where a postoperative adhesion barrier is required. Copyright (c) 2013 John Wiley & Sons, Ltd.en_US
dc.description.sponsorshipTurkish Academy of SciencesTurkish Academy of Sciencesen_US
dc.description.sponsorshipH.M.A. would like to thank B.M.T. Calsis for donation of the monomers. E.P. was supported by the Turkish Academy of Sciences as a full member. The authors thank Mr T. Vural and Mr C. Bayram for SEM analysis and Mr T. Cirak for his help in drawing the figures. PHB electrospun scaffolds were kindly donated by Dr M. Demirbilek.en_US
dc.language.isoengen_US
dc.publisherWiley-Blackwellen_US
dc.relation.isversionof10.1002/term.1759en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectelastomersen_US
dc.subjectglycerolen_US
dc.subjectsebacic aciden_US
dc.subjectepsilon-caprolactoneen_US
dc.subjectself-healingen_US
dc.subjectsupercritical CO2en_US
dc.titleSynthesis and characterization of poly(glycerol-co-sebacate-co-epsilon-caprolactone) elastomersen_US
dc.typearticleen_US
dc.contributor.departmentKırıkkale Üniversitesien_US
dc.identifier.volume10en_US
dc.identifier.issue1en_US
dc.identifier.startpageE14en_US
dc.identifier.endpageE22en_US
dc.relation.journalJournal Of Tissue Engineering And Regenerative Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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