Ara
Toplam kayıt 35, listelenen: 11-20
SAR Evaluation of Disubstituted Tacrine Analogues as Promising Cholinesterase and Carbonic Anhydrase Inhibitors
(Assoc Pharmaceutical Teachers India, 2019)
Background: The inhibition of both hydrolysis products of acetylcholine (ACh), Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), is essential for successful treatment of Alzhemier patients. Objectives: This ...
Synthesis, characterization, crystal structures, theoretical calculations and biological evaluations of novel substituted tacrine derivatives as cholinesterase and carbonic anhydrase enzymes inhibitors
(Elsevier Science Bv, 2019)
The six and seven hydrocycle membered disilylanilino acridine (tacrine) analogues (9-11) were synthesized by one-pot procedures. The structures of novel silyl tacrine derivatives were characterized by NMR spectroscopy, ...
The adaptation of the pedagogical knowledge and skills survey into Turkish: Validity and reliability study
(Mehmet Tekerek, 2019)
This research aims to adapt the Pedagogical Knowledge and Skills in Teaching (PKST) survey developed by Wong, Chong, Choy and Lim (2012) to Turkish. The participants of the study are 830 4th year students of education ...
Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties
(Wiley-V C H Verlag Gmbh, 2019)
The synthesis, characterization, aggregation behavior, theoretical studies, and investigation of antimicrobial, antidiabetic, and anticholinergic properties of 4-(2-(5-amino-4-(4-bromophenyl)-3-methyl-1H-pyrazol-1-yl)eth ...
Synthesis of novel cyano quinoline derivatives
(Pergamon-Elsevier Science Ltd, 2015)
6,8-Dibromo-1,2,3,4-tetrahydroquinoline (2) and 3,6,8-tribromoquinoline (3) were converted into the corresponding cyano derivatives via copper assisted nucleophilic substitution reactions. While bromination of 6-bromo-8- ...
Synthesis Of Brominated Quinolines
(Yildiz Technical Univ, 2015)
this study, bromination reactions of 1,2,3,4-tetrahydroquinoline by molecular bromine and aromatization reactions of brominated tetrahydroquinolines were reinvestigated. Optimal reaction conditions were established for ...
Effect of heat treatments on the microhardness and tensile strength of Al-0.25 wt.% Zr alloy
(Elsevier Science Sa, 2015)
In the present work, the effect of heat treatments on the microhardness and tensile properties of the Al-0.25 Zr (wt.%) alloy have been investigated. The Al-0.25 Zr (wt.%) alloy was melted in a vacuum furnace, and the ...
Augmented reality in science laboratories: The effects of augmented reality on university students' laboratory skills and attitudes toward science laboratories
(Pergamon-Elsevier Science Ltd, 2016)
This study investigated the effects of the use of augmented reality (AR) technologies in science laboratories on university students' laboratory skills and attitudes towards laboratories. A quasi-experimental pre-test/post-test ...
Convenient synthesis of disubstituted tacrine derivatives via electrophilic and copper induced reactions
(Pergamon-Elsevier Science Ltd, 2016)
The bromination of 2-aminobenzonitrile (2) with molecular bromine (2 equiv) furnished 2-amino-3,5-dibromobenzonitrile (7) in 98% yield. One-pot syntheses are described for dibromotacrine derivatives (6,14-18) utilizing ...
Effect of heat treatment on the microstructures and mechanical properties of Al-5.5Zn-2.5Mg alloy
(Elsevier Science Sa, 2016)
The Al-5.5 Zn-2.5 Mg (wt%) ternary alloy was prepared using a vacuum melting furnace and a casting furnace. Microstructural and mechanical properties of the alloy were investigated as-cast and under heat-treated conditions. ...