Turk, MustafaTamer, UgurAlver, ErolCiftci, HakanMetin, Aysegul U.Karahan, Siyami2020-06-252020-06-252013closedAccess2169-14012169-141Xhttps://doi.org/10.3109/21691401.2012.761228https://hdl.handle.net/20.500.12587/5405Tamer, Ugur/0000-0001-9989-6123The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929-fibroblasts. L929-fibroblasts were seeded either onto Ch or Ch/AuNPs scaffolds. The Ch/AuNPs scaffold exhibited a higher cell proliferation and growth rate. The cytotoxicity test determined trypan blue staining indicated that Ch scaffolds devoid of AuNPs expressed almost no toxicity while the Ch/AuNPs composite scaffolds expressed a very limited toxicity only at higher doses. The Ch/AuNPs scaffold promotes cell attachment, growth and proliferation with almost no cytotoxicity.eninfo:eu-repo/semantics/closedAccesschitosancytotoxicitygold nanorodL929-fibroblastsArticle41639540110.3109/21691401.2012.7612282-s2.0-8488966560323330692Q1WOS:000329843900007Q4