Apan, Teoman ZaferIseri, LatifeAksoy, AltanGüliter, Sefa2020-06-252020-06-252008Apan, T. & işeri, L. & Aksoy, A. & Güliter, S. (2008). The Antibody Response to Helicobacter pylori in the Sera from a Rural Population in the Central Anatolia Region of Turkey. Journal of Health Science - J HEALTH SCI. 54(6), 671-674. 10.1248/jhs.54.671.1344-97021347-5207https://doi.org/10.1248/jhs.54.671https://hdl.handle.net/20.500.12587/4048Helicobacter pylori (H. pylori) infection is common worldwide. Although the seropositivity of H. pylori rates has been unclear in the Turkish population. In this study, anti-H. pylori IgG seroprevalence and anti-cytotoxin-associated gene A (CagA) IgG positivity were evaluated. The sera of 880 people without gastrointestinal symptoms (384 males, 496 females) were tested for anti-H. pylori IgG and anti-CagA IgG antibodies by enzyme linked immunoassay method. Anti-H. pylori IgG antibodies were positive in 263 sera (41%) and their rates increased with age. The seroprevalence of anti-H. pylori IgG was higher in females (43.8%) than in males (38%). Of the anti-H. pylori IgG positive sera, 194 (53%) were also positive for anti-CagA IgG. The anti-CagA IgG positivity did not significantly differ with age. However, the lowest rate (46.6%) was determined among individuals 2029 years of age and the highest rate (62.5%) among individuals over 60 years age. Anti-CagA IgG positivity rates were higher in males (87.5%) than in females (37.5%).eninfo:eu-repo/semantics/openAccessHelicobacter pyloricytotoxin-associated gene Aanti-Helicobacter pylori IgGArticle54667167410.1248/jhs.54.6712-s2.0-57349119125N/AWOS:000261223600009Q4