Baççıoğlu, AyşeGünal, NesimiKalpaklıoğlu, FüsunDural, KorayÖzpolat, Berkant2025-01-212025-01-2120131309-07201309-2014https://doi.org/10.4328/JCAM.2347https://hdl.handle.net/20.500.12587/24281Pulmonary langerhans cell histiocytosis is a rare reactive disorder with unclear pathogenesis. 16-year-old male patient complained about shortness of breath induced with exercise, non-productive cough, and intermittent chest pain for one year. Pulmonary function tests were in restrictive nature. There were multiple air cysts in lung parenchyma smaller than one cm and minimal pneumothorax on the left hemithorax in high resolution computed tomography of thorax. There was no hypoxemia in arterial blood gas analysis, and no pulmonary hypertension in echocardiography. Pulmonary langerhans cell histiocytosis was diagnosed with clinical features and typical radiographic appearance. Existence of multisystem langerhans cell histiocytosis was excluded thorough a detailed history, comprehensive physical examination, and baseline radiographic, blood and urine tests. He was recommended to quit smoking and close follow-up was planned. A tube thoracostomy was performed for left sided total pneumothorax one month later, and blood patch pleurodesis was done due to persistent air leakage with a successful outcome. As far as we know this is the first case report of pulmonary langerhans cell histiocytosis who was treated with autologous blood pleurodesis in the literature.trinfo:eu-repo/semantics/openAccessBlood Patch Pleurodesis; Histiocytosis; PneumothoraxArticle436436710.4328/JCAM.2347WOS:000215555000008N/A