Midi, AhmetKumandas, AliEkici, HusamettinKilic, YusufOzgocmen, Ruchan2025-01-212025-01-2120211302-00722147-2688https://doi.org/10.4274/haseki.galenos.2021.6506https://search.trdizin.gov.tr/tr/yayin/detay424534https://hdl.handle.net/20.500.12587/23937Aim: The purpose of this study is to evaluate the hemostatic efficacy of a novel plant originated blood stopper which is called Algan Hemostatic Agent (AHA) in uncontrolled kidney incision bleeding model. Methods: The study was conducted with thirty-two rats 5-7 weeks old. The rats were randomly divided into 4 groups, each consisting of eight rats (Group 1: heparinized saline, 2: heparinized AHA, 3: non-heparinized saline, 4: non-heparinized AHA). Experimental kidney incision was made, and saline soaked sponge was applied to the control group and AHA to the study group. Results: The duration of bleeding was significantly shorter in the AHA group compared to the control group. The AHA has controlled the bleeding in the heparinized and non-heparinized groups 5 +/- 1.19 and 3 +/- 0.91 seconds respectively (p<0.001). In the control group, hemorrhage was controlled in the heparinized and non-heparinized group 180.6 +/- 25.4 and 125.4 +/- 21 seconds respectively. Conclusion: This study demonstrated that the AHA is useful in controlling bleeding in the Rat kidney incision model.eninfo:eu-repo/semantics/openAccessAlgan hemostatic agent; hemostasis; rats; kidney; bleedingArticle591434710.4274/haseki.galenos.2021.65062-s2.0-85101311748Q3424534WOS:000658757400007N/A