Apan, AlpaslanSari, FilizEkmekci, Alp Burak2020-06-252020-06-252010Apan, A., Sarı, F. And Ekmekçi, A. B. (2010) "Single shot “3-in-1” femoral nerve blockade with 0.25% or 0.375% levobupivacaine provides similar postoperative analgesia for total knee replacement," Turkish Journal of Medical Sciences: Vol. 40(1), 77-82.1300-01441303-6165https://doi.org/10.3906/sag-0812-39https://hdl.handle.net/20.500.12587/4807Aim: To compare postoperative analgesia provided by single shot "3-in-1" femoral nerve blockade using 0.25% or 0.375% levobupivacaine in preceding with spinal anesthesia for unilateral total knee replacement surgery. Materials and methods: Forty consenting patients undergoing unilateral total knee arthroplasty were included in this prospective randomized study. Spinal anesthesia was achieved with 15 mg plain bupivacaine at the L3-4 or L4-5 interspace. After resolution of the spinal anesthesia, patients were randomized into 2 groups: "3-in-1" femoral nerve blocks were performed using 30 m L of 0.25% levobupivacaine (Group 1, n = 20) or 0.375% levobupivacaine (Group 2, n = 20). Pain was assessed by visual analogue scale (VAS). The total morphine consumption and the side effect profile were compared during the postoperative period. Results: There were no significant differences between the 2 study groups with respect to characteristics or intraoperative variables. Furthermore, sensory block periods and time to first pain sensation, VAS, and morphine consumption for 24 h (Group 1: 19.7 +/- 9.2, Group 2:20.6 +/- 12.1 mg) were similar. Pain scales and range of motion during rehabilitation period and side effects were also comparable. Conclusion: Our results indicate that the augmenting concentration did not influence the clinical outcome when single shot "3-in-1" femoral nerve block was performed with 0.25% or 0.375% levobupivacaine in total knee arthroplasty.eninfo:eu-repo/semantics/openAccessAnesthetic techniquesregionalfemoral nerve blockpainpostoperativelevobupivacaineSingle shot "3-in-1" femoral nerve blockade with 0.25% or 0.375% levobupivacaine provides similar postoperative analgesia for total knee replacementArticle401778210.3906/sag-0812-392-s2.0-76149139755Q198261WOS:000275833900012Q4