Sarak, TanerKaradeniz, Muhammed2020-06-252020-06-252019Sarak T., Karadeniz M. (2019). The relationship between serum NT-proBNP levels and severity of coronary artery disease assessed by SYNTAX score in patients with acute myocardial infarction. Turkish Journal of Medical Sciences, 49(5), 1366 - 13731300-01441303-6165https://doi.org/10.3906/sag-1902-26https://hdl.handle.net/20.500.12587/7898Background/aim: In the present study, we aimed to investigate the relationship between NT-proBNP and SYNTAX score, which is a measure of the complexity of coronary artery disease. Materials and methods: We enrolled 405 consecutive patients with myocardial infarction who underwent coronary angiographic examination. Patients were divided into 3 groups according to their SYNTAX scores. Those with SYNTAX score <= 22 were included in the low SYNTAX score group (LSTX), those with a score of 23-32 were included in the intermediate SYNTAX score group (ISTX), and those with a score of >= 33 were included in the high SYNTAX score group (HSTX). Results: NT-proBNP levels were found to be significantly higher in the HSTX group compared to the other groups (P < 0.001) and in the ISTX group compared to the LSTX group (P < 0.001). The NT-proBNP levels demonstrated an increase from low SYNTAX score to high SYNTAX score tertiles. Conclusions: NT-ProBNP levels in patients with myocardial infarction on admission were independently associated with extent, severity, and complexity of coronary atherosclerosis as assessed by SYNTAX score.eninfo:eu-repo/semantics/openAccessMyocardial infarctionNT-proBNPseverity of coronary artery diseaseArticle4951366137310.3906/sag-1902-262-s2.0-8507407471031648513Q1336714WOS:000504050500015Q4