Senol, AliAkanbong, Elisha ApatewenSudagidan, MertDevrim, Alparslan Kadir2025-01-212025-01-2120210035-3930https://doi.org/10.33224/rrch.2021.66.8-9.02https://hdl.handle.net/20.500.12587/24528Deoxyribonucleic acid (DNA), which leads the biological synthesis of proteins and enzymes in living cells and carries genetic information, is a potential target for binding many molecules such as metals, metal complexes, anticancer drugs, and some harmful chemicals. Molecules that bind to DNA by covalent or non-covalent intercalation, electrostatic interaction, and groove binding cause disruption in the double-stranded DNA structure. This situation is of great importance in studies conducted in the field of pharmacy to increase the effectiveness of antitumor and antiviral drugs, in DNA-based disease diagnosis and determination of toxicity properties of metal complexes. The purpose of this review is to evaluate the interactions of DNA-metal complexes and provide information about their determined biological activities.eninfo:eu-repo/semantics/closedAccessDNA; metal complexes; DNA-metal interaction; potential drug effectReview Article668-970171110.33224/rrch.2021.66.8-9.022-s2.0-85136829499Q4WOS:000835326300002Q4