Pinar, TevfikAkdur, RecepTunçbilek, ArslanAltundağ, KadriCengiz, Mustafa2020-06-252020-06-252007closedAccess0027-96841943-4693https://hdl.handle.net/20.500.12587/4005Objective: The objective of this study was to investigate the relationship between occupation and head and neck cancers. Patients and Methods: In this case-control study, 206 Turkish patients with head and neck cancers comprised the case group. The control group consisted of 206 age- and sex-matched patients without malignant disease. All patients completed a questionnaire regarding occupation; tobacco and alcohol consumption; educational status; and history of any systemic disease, benign head and neck disease, and cancer among family members. High-risk jobs were considered those in the industries of construction, wood, mining, metal, chemistry and agriculture. Results: Patients with head and neck cancers worked in high-risk occupations more frequently than did controls [odds ratio (OR): 3.42, p < 0.05]. Cancer risk decreased with the increase in time interval between quitting the high-risk job and time of interview. Smokers were at higher risk than nonsmokers (OR: 3.33, p < 0.05). The risk was also higher in patients who drank alcohol regularly (OR: 1.59, p < 0.05). However, occupation was found to be an independent high-risk factor for head and neck cancers in regression analysis. Frequency of benign head and neck disease and family history of cancer were not significant risk factors (p > 0.05). Conclusion: Our analysis showed that occupation and smoking were significant independent risk factors for the development of head and neck cancers among workers.eninfo:eu-repo/semantics/closedAccessheadnecktumorsrisk factorssmokingalcoholArticle99164+2-s2.0-3384658852317304970Q1WOS:000243863500009N/A