Barış, KubilayOlgun, EbruBadem, Nermin Dindar2025-01-212025-01-2120232149-9063https://doi.org/10.4274/meandros.galenos.2021.05900https://search.trdizin.gov.tr/tr/yayin/detay1255017https://hdl.handle.net/20.500.12587/23891Objective: The aim of this study was to evaluate the effects of different laser systems in smokers and nonsmokers with peri-implantitis. Materials and Methods: Subjects were divided into six groups according to the study protocol: Group 1: Smokers who underwent diode laser application; group 2: Erbium, chromium: Yttrium, scandium, gallium, garnet (Er, Cr: YSGG) laser application. Group 3: smokers undergoing Erbium: Yttrium-aluminum-garnet (Er: YAG) laser application; group 4: non-smokers undergoing diode laser application; group 5: non-smokers undergoing Er,Cr: YSGG laser application; and group 6: non-smokers undergoing Er: YAG laser application. Peri-implant sulcus depth (SD), clinical attachment level (CAL), suppuration, modified plaque index (mPI), gingival index (GI), and modified sulcus bleeding index (mSBI) were recorded, and peri-implant sulcus fluid (PISF) was collected to evaluate osteocalcin. Results: There were statistically significant differences in the baseline and six-month SD, CAL, mPI, GI, mSBI measurements, and osteocalcin values in all groups (p<0.05). Conclusion: Laser applications for treating peri-implantitis have significantly improved clinical parameters and PISF osteocalcin levels.eninfo:eu-repo/semantics/openAccessBone; dental implants; lasers; osteocalcin; peri-implantitis; risk factorsArticle24318018610.4274/meandros.galenos.2021.059001255017WOS:001154629400001Q4