Bas, Ahmet YagmurDemirel, NihalKoc, EsinIsik, Dilek UlubasHirfanoglu, Ibrahim MuratTunc, TuranHocaoglu, Mumin2020-06-252020-06-252018Bas AY, Demirel N, Koc E on behalf of the TR-ROP Study Group, et alIncidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care unitsBritish Journal of Ophthalmology 2018;102:1711-1716.0007-11611468-2079https://doi.org/10.1136/bjophthalmol-2017-311789https://hdl.handle.net/20.500.12587/7226ceylan, nihan aksu/0000-0003-3724-7659; Ors, Rahmi/0000-0002-9089-1067; Beken, Serdar/0000-0002-8609-2684; Unsal, Ayse Ipek Akyuz/0000-0001-5260-674X; Kimyon, Sabit/0000-0001-9194-9841; Seven, Erbil/0000-0001-5629-291X; Ozkan, Hasan/0000-0003-2542-7441; Kirgiz, Ahmet/0000-0001-7498-3693; Kiray, Gulunay/0000-0002-9618-9797; BAS, AHMET YAGMUR/0000-0002-1329-2167; Satirtav, Gunhal/0000-0003-4157-2876Background To evaluate the prevalence, risk factors and treatment of retinopathy of prematurity (ROP) in Turkey and to establish screening criteria for this condition. Methods A prospective cohort study (TR-ROP) was performed between 1 April 2016 and 30 April 2017 in 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)=1500 g or gestational age (GA)<= 32 weeks and those with a BW> 1500 g or GA> 32 weeks with an unstable clinical course were included in the study. Predictors for the development of ROP were determined by logistic regression analyses. Results The TR-ROP study included 6115 infants: 4964 (81%) with a GA <= 32 weeks and 1151 (19%) with a GA>32 weeks. Overall, 27% had any stage of ROP and 6.7% had severe ROP. A lower BW, smaller GA, total days on oxygen, late-onset sepsis, frequency of red blood cell transfusions and relative weight gain were identified as independent risk factors for severe ROP in infants with a BW=1500 g. Of all infants, 414 needed treatment and 395 (95.4%) of the treated infants had a BW <= 1500 g. Sixty-six (16%) of the treated infants did not fulfil the Early Treatment for Retinopathy of Prematurity requirements for treatment. Conclusions Screening of infants with a GA <= 34 weeks or a BW<1700 g appears to be appropriate in Turkey. Monitoring standards of neonatal care and conducting quality improvement projects across the country are recommended to improve neonatal outcomes in Turkish NICUs.eninfo:eu-repo/semantics/openAccessArticle102121711171610.1136/bjophthalmol-2017-31178929519879WOS:000456552200020Q1