Arikan, SevketSimsek, OzkanKalender, HakanEssiz, DincAtmaca, NurgulKabakci, RuhiBilmen, Fatih Sultan2020-06-252020-06-252017Arikan, S., Simsek, O., Kalender, H., Essiz, D., Atmaca, N., Kabakci, R. ve Bilmen, F. S. (2017). Effects Of Acetamiprid, Methomyl, And Deltamethrin On Steroidogenesis In Cultured Bovine Luteal Cells. Fresenius Environmental Bulletin, 26(5), 3280–3284.1018-46191610-2304https://hdl.handle.net/20.500.12587/7150KABAKCI, Ruhi/0000-0001-9131-0933Acetamiprid, methomyl, and deltamethrinare widely used insecticides in agriculture and industry; thus, livestock may receive substantial exposure to such substances. This study was designed to evaluate the effect of these agents on bovine luteal cell steroidogenesis.Cells were incubated with acetamiprid (0.1 mM, 1 mM, or 10 mM), methomyl (0.1 mM, 1 mM, or 10 mM), or deltamethrin (0.01 mM, 0.1 mM, or 1 mM) for 5 days. Incubation with 1 mMacetamiprid resulted in significantly reducedpro-gesterone production by day 5. Incubation with 1 mM methomyl had no effect on progesterone pro-ductionby day 3 but did result in significant inhibi-tionby day 5. Incubation in 0.1 mM and 1 mMdelta-methrin resulted in significant reduction on both days 3 and 5. All three insecticides diminish luteal progesterone synthesis, with rank order methomyl<acetamiprid<deltamethrin.Excessive exposure to these agents, particularly deltamethrin, may weaken the breeding potential of bovine livestock.eninfo:eu-repo/semantics/openAccessAcetamipridmethomyldeltamethrinbovine luteal cellsprogesteroneArticle26532803284WOS:000403134800022Q4