Kultur, TurgutCiftci, AydinOkumus, MuyesserDogan, MuratDurmaz, Senay ArikanNeselioglu, SalimErel, Ozcan2021-01-142021-01-1420202587-0823https://doi.org/10.5606/tftrd.2020.3301https://hdl.handle.net/20.500.12587/12871Objectives: This study aims to investigate the effect of chiropractic manipulative treatment on sacroiliac joint dysfunction (SIJD) and its relationship to oxidative stress (OXS) parameters. Patients and methods: Thirty-three patients diagnosed with SIJD (20 males, 13 females; mean age 36.3 +/- 9.7 years; range, 18 to 60 years) and 30 healthy volunteers (20 males, 10 females; mean age 36.4 +/- 12.2 years; range, 20 to 57 years) were included in this cross-sectional, case-control study conducted between February 2017 and September 2017. Manipulation was applied to the patients once a week for a duration of four weeks. The patients were evaluated at pre-treatment and one month after treatment with visual analog scale, SIJD test, and total thiol, native thiol, disulphide, and ischemia-modified albumin (IMA) as OXS indicators. Results: Prior to treatment, we demonstrated that serum native thiol (mu mol/L) and total thiol (mu mol/L) levels in the patient group were lower compared to control subjects (p=0.03 and p=0.02, respectively). Serum IMA levels were higher in the patient group (p=0.01). There was no change in OXS parameters after manipulative treatment in the patient group. Conclusion: Manipulation is useful in SIJD. Thiol/disulphide homeostasis and serum IMA levels may be used to measure the OXS in patients with SIJD.eninfo:eu-repo/semantics/openAccessChronic painischemia-modified albuminmanipulative treatmentsacroiliac joint dysfunctionthiol/disulphide homeostasisArticle66217618310.5606/tftrd.2020.33012-s2.0-8509074215332760895Q2410788WOS:000537288500010Q4