Demirbaş, AbdullahElmas, Ömer FarukAkdeniz, Necmettin2025-01-212025-01-212022978-100051994-5978-036761499-7https://doi.org/10.1201/9781003105268-19https://hdl.handle.net/20.500.12587/23237Most benign cutaneous neoplasms can be diagnosed clinically. If the diagnosis is uncertain clinically, especially when there have been unexpected changes in the appearance of the lesion, a biopsy is indicated. Lesions are small hyperpigmented macules with a diameter generally not exceeding 5 mm. The melanotic macule is a benign hyperpigmentation of mucous membranes found in about 3% of the general population. There is an increase in focal melanin accumulation without an increase in melanocytes. The most important differential diagnosis of acquired melanocytic lesions is melanoma. Histologically, lesions differ from melanoma by having small nucleolus of the melanocytes, absence of atypical mitoses, uniformity of cells, normal maturation, and nesting. Destructive methods, such as cryotherapy, curettage, laser, shave excision, electrocautery, and chemical peels, can be performed for aesthetic purposes. Moles are a common finding that require intervention only when there is concern for a malignancy or when they are cosmetically unacceptable. © 2022 Taylor & Francis Group, LLC.eninfo:eu-repo/semantics/closedAccessBook Chapter23024510.1201/9781003105268-192-s2.0-85133088702N/A