Soyer, TutkuAydos, Tolga ResatAktuna, ZuhalKorkut, OguzhanOzmanoglu, GoekhanHancerliogullari, OeymenCakmak, Murat2020-06-252020-06-252009Soyer, T., Aydos, T. R., Aktuna, Z., Korkut, O., Osmanoğlu, G., Hançerlioğulları, K. Ö., Çakmak, M. (2009). The effect of experimentally induced carbon dioxide pneumoperitoneum on intra-abdominal and intra-esophageal pH. Turkish Journal of Medical Sciences, 39(5), 709 - 712.1300-0144https://doi.org/10.3906/sag-0807-18https://hdl.handle.net/20.500.12587/4377Aydos, Tolga Resat/0000-0002-1832-9336; Soyer, Tutku/0000-0003-1505-6042Aim: An experimental study was performed to evaluate the effect of CO2 pneumoperitoneum on intra-abdominal (IA) and intra-esophageal (IE) pH. Material and methods: The study included 18 Wistar rats. In the control group (n = 6) a pH catheter was inserted into the peritoneal cavity via a left upper quadrant incision and another catheter was inserted into the lower esophagus via the oral route. Pre- and post-insufflation IA and IE pH were recorded every 5 min for 1 h. In the experimental groups, in addition to pH catheters, a 16-G catheter was inserted into the abdomen above the umbilicus. In the O-2 group (n = 6) 95% O-2 and 5% CO2 were insufflated with a pressure of 10 mmHg. In the CO2 group (n = 6), CO2 was insufflated with the same pressure and duration. Results: In the CO2 group, IA and IE pH values significantly decreased (P < 0.05). IA pH values decreased in the CO2 group when compared to the control and O-2 groups (P < 0.05). There was not a significant difference in IE pH between the CO2 group and the other groups. Conclusion: CO2 insufflation decreased IA pH values. Decreased pH values obtained with continuous recordings of the esophagus may have been related to increases in intra-abdominal pressure, rather than the metabolic effects of CO2 pneumoperitoneum.eninfo:eu-repo/semantics/closedAccessCarbon dioxidepHpneumoperitoneumesophagusabdomenArticle39570971210.3906/sag-0807-182-s2.0-70350444430Q196901WOS:000272499100007Q4