Derhem, BakiKarahan, İrfan2025-01-212025-01-2120231307-10681308-5271https://doi.org/10.5578/ced.20239916https://search.trdizin.gov.tr/tr/yayin/detay1178161https://hdl.handle.net/20.500.12587/23821Objective: Obesity is a serious health problem, has reached pandemic proportions and represents a major risk for several comorbidities. Some of the serum markers are considered to be associated with low-grade chronic inflammation. Neutrophil to lymphocyte ratio (NLR) is a new and cost-effective marker for the detection of subclinical inflammation that correlates with C-reactive protein (CRP) levels. The objectives of this study were to examine the relation between children's BMI and the bio-markers of early inflammatory predictors.Material and Methods: The retrospective study included 176 children aged 5-18 years who applied to a primary care setting in Turkiye be-tween January 2019 and March 2019. Participants with BMIs between 85-95 percentiles were defined as overweight and those over 95 per-centiles as obese. For all groups, hemogram parameters, cell volumes, and ratios were evaluated and compared. In addition, NLR and PLR were compared.Results: We found that neutrophil count and NLR were significantly different between the normal weight and overweight/obese groups (p= 0.001, p< 0.001 respectively) while hemoglobin, WBC, MPV, MCV, RDW, and PLR were similar in hemogram evaluation.Conclusion: Obesity is associated with low-grade inflammation levels and is reaching alarming rates among both children and adults. Our study suggested that neutrophil counts and NLR were significantly higher in overweight/obese children. Obesity-related studies involving pediatric patients are crucial to developing appropriate methods for preventing the development of further complications in adulthood.eninfo:eu-repo/semantics/openAccessObesity; childhood; neutrophil to lymphocyte ratio; platelet to lymphocyte ratioArticle17191310.5578/ced.202399162-s2.0-85153316302Q41178161WOS:000975510800002Q4