Gunduz, OzgurEmeksiz, Mehmet CanAtasoy, PinarKidir, MehtapYalcin, SelimDemirkan, Serkan2020-06-252020-06-252016Gündüz, Ö., Emeksiz, M. C., Atasoy, P., Kidir, M., Yalçin, S., & Demirkan, S. (2017). Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach. Dermatology reports, 8(1), 6819.2036-73922036-7406https://doi.org/10.4081/dr.2016.6819https://hdl.handle.net/20.500.12587/6790emeksiz, can/0000-0002-0933-4619; Gunduz, Ozgur/0000-0003-1021-5219Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient's head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed.eninfo:eu-repo/semantics/openAccessSignet-ring cellmetastatic skin cancerimmunohistochemistryReview Article81151810.4081/dr.2016.68192-s2.0-8506236054528326183Q3WOS:000473535900004N/A