Yüksel, UlaşÖğden, MustafaAkkaya, SüleymanKısa, ÜçlerBakar, BülentÖzveren, Mehmet Faik2025-01-212025-01-2120202148-9645https://doi.org/10.24938/kutfd.792597https://search.trdizin.gov.tr/tr/yayin/detay/421512https://hdl.handle.net/20.500.12587/23084Objective: In this study, the economic cost, diagnostic andprognostic laboratory markers of lumbar spondylodiscitis, whichemerged as a complication after surgical intervention in thelumbar region, were investigated.Material and Methods: Age and gender of the patients wererecorded. Furthermore, surgical intervention type (spinalinstrumentation, lumbar discectomy), biopsy results of infectedtissue, concomitant morbidities, duration of hospital stay andmicroorganism growth in culture materials were evaluated inpatients. In addition, values of serum C-reactive protein (CRP)level, erythrocyte sedimentation rate (ESR), leukocyte, neutrophiland lymphocyte count which were obtained from these patients atadmission to hospital and at discharge from hospital wererecorded. Moreover, treatment costs of these patients wereexamined.Results: Nine patients (women=7, men=2) with a mean age of58±14.92 years were included in this study. All parameters ofpatients were not different in terms of surgical intervention type.However, when the patients were discharged from the hospital,their ESR and neutrophil counts decreased and lymphocyte countincreased in all of them. Although CRP level values decreased asnumerical value at discharge, this decrease was not statisticallysignificant. Correlation analysis showed that length of hospitalstay and tissue biopsy performed to the patients increased theeconomic cost.Conclusion: It was concluded that any routine laboratoryparameter investigated in this study could not be a validbiomarker for diagnosis and follow-up of spondylodiscitis thatemerged after surgical intervention. On the other hand, it wasconcluded that diagnosis and treatment of this disease, whoseprevalence is increasing, may have a high economic cost forpatients and countries.eninfo:eu-repo/semantics/openAccessTıbbi Araştırmalar DeneyselGenel ve Dahili TıpPatolojiArticle22334134710.24938/kutfd.792597421512