Keceli, Huseyin GencayAylikci, Bahadir UgurKoseoglu, SerhatDolgun, Anil2020-06-252020-06-252015closedAccess0303-69791600-051Xhttps://doi.org/10.1111/jcpe.12404https://hdl.handle.net/20.500.12587/6148Dolgun, Anil Barak/0000-0002-2693-0666; Bayram, Cem/0000-0001-8717-4668AimEvaluating effectiveness of a medicinal plant extract (MPE) in achieving haemostasis and early wound healing at free gingival graft (FGG) donor site in a randomized controlled fashion. MethodsForty patients requiring FGG at lower anterior area were randomly assigned into two groups. FGG was performed to all patients and following graft procurement; wet gauze (WG) was applied alone (control: WG group) or with MPE (test: MPE+WG group) for haemostasis. Donor site working time, bleeding (BLE), colour match (CM), pain, epithelization (EP) and sensation loss (SL) were evaluated. ResultsThirty-three participants completed a 6-month period study. In the test group, primary BLE was shorter (p<0.001) and fewer individuals showed secondary BLE during 3days (p<0.001). During the 6days, pain scores were higher in WG patients (p<0.05). Later on, no inter-group difference was observed. EP was relatively faster (p<0.001) and CM was slightly better (p<0.05) in MPE+WG group. ConclusionMPE provided faster and continuous haemostasis that made a positive contribution to the early soft tissue healing to some extent but due to limitations; further trials are needed to demonstrate the efficiency of this material.eninfo:eu-repo/semantics/closedAccessdonor sitefree gingival grafthaemostasispalatal healingwound healingArticle42658258910.1111/jcpe.124042-s2.0-8493156187025892528Q1WOS:000356367300011Q1