Yazar "Acik, Leyla" için listeleme
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Antimicrobial, antioxidant, cytotoxic and apoptotic activities of Satureja khuzestanica
Soltanzadeh, Hossein; Acik, Leyla; Turk, Mustafa; Houshmand, Massoud; Shahsavari, Gholamreza (Gazi Univ, Fac Med, 2018)Objective: Natural products with antimicrobial effect are currently investigated in order to eliminate the use of synthetic antibiotics that cause the resistance of microorganisms. This study determines the antibacterial, ... -
Characterisation of coagulase positive Staphylococcus species isolated from bovine mastitis using protein and plasmid patterns
Arslan, Emine; Celebi, Ayten; Acik, Leyla; Ucan, Uckun Sait (Scientific Technical Research Council Turkey-Tubitak, 2009)The objective of this work was to study the protein patterns, plasmid profiles, and antibiotic susceptibility of Staphylococcus intermedius and Staphylococcus aureus isolates originating from mastitic mammary glands of ... -
Cytotoxicity and DNA interactions of some platinum(II) complexes with substituted benzimidazole ligands
Ozcelik, Azime Berna; Utku, Semra; Gumus, Fatma; Keskin, Ayten Celebi; Acik, Leyla; Yilmaz, Sukran; Ozgungor, Adeviye (Informa Healthcare, 2012)In the present study, four Pt(II) complexes with 2-ethyl (1)/or benzyl (2)/or p-chlorobenzyl (3)/or 2-phenoxymethyl (4) benzimidazole carrier ligands were evaluated for their in vitro cytotoxic activities against the human ... -
Dispiro-4-bromobenzylaminophosphazenes: Synthesis reactions, spectroscopic and chromatographic properties, crystal structures, biological, and cytotoxic activities
Kuzey, Nur Guven; Ozgur, Mehtap; Asmafiliz, Nuran; Acik, Leyla; Aydin, Betul; Hokelek, Tuncer; Cerci, Aytuna (Amer Chemical Soc, 2019)… -
Genetic Differentiation of Lactobacillus delbrueckii subsp bulgaricus and Streptococcus thermophilus Strains Isolated from Raw Milk Samples Collected from Different Regions of Turkey
Yilmaz, Remziye; Temiz, Ayhan; Acik, Leyla; Keskin, Ayten Celebi (Taylor & Francis Inc, 2015)Yogurt is a fermented milk product produced by two homofermentative lactic acid bacteria, Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus. It is consumed throughout the world as a healthy, ... -
Investigation of potential virulence genes and antibiotic resistance characteristics of Enterococcus faecalis isolates from human milk and colostrum samples
Togay, Sine Ozmen; Temiz, Ayhan; Celebi, Ayten; Acik, Leyla; Yalcin, Siddika Songul (Tubitak Scientific & Technical Research Council Turkey, 2014)Enterococci may improve the typical taste and flavor of fermented foods through their proteolytic and lipolytic activities. However, some enterococcal strains are recognized as nosocomial pathogens, which have virulence ... -
Novel fluorescent coumarin-thiophene-derived Schiff bases: Synthesis, effects of substituents, photophysical properties, DFT calculations, and biological activities
Yahaya, Issah; Chemchem, Meryem; Aydiner, Burcu; Seferoglu, Nurgul; Tepe, Fulya Erva; Acik, Leyla; Seferoglu, Zeynel (Elsevier Science Sa, 2019)Novel fluorescent coumarin-thiophene appended Schiff bases have been synthesized in good yields (76-89%). The effects of substitution on the fluorescent intensity and solubility of the molecules were examined with experimental ... -
Phosphorus nitrogen compounds: Part 34. Syntheses, structural investigations, cytotoxic and biological activities of spiro-ansa-spiro and spiro-bino-spiro tetrameric phosphazene derivatives
Berberoglu, Ipek; Asmafiliz, Nuran; Kilic, Zeynel; Hokelek, Tuncer; Koc, L. Yasemin; Acik, Leyla; Dal, Hakan (Elsevier Science Sa, 2016)The reactions of N4P4Cl8 with the symmetric N2N2 (1-3) and N2O2 (4) bulky ligands gave partly substituted 2,4-sas (5 and 6), 2,6-sas (7-10) and sbs (11-14) tetrameric phosphazene derivatives. The 2,4-sas-5, 2,6-sas-8 and ... -
Phosphorus-nitrogen compounds part 33: in vitro cytotoxic and antimicrobial activities, DNA interactions, syntheses, and structural investigations of new mono(4-nitrobenzyl)spirocyclotriphosphazenes
Okumus, Aytug; Akbas, Huseyin; Kilic, Zeynel; Koc, L. Yasemin; Acik, Leyla; Aydin, Betul; Dal, Hakan (Springer, 2016)The condensation reactions of hexachlorocyclotriphosphazene, N3P3Cl6, with N-alkyl-N'-mono(4-nitrobenzyl)diamines (1-3), NO2PhCH2NH(CH2) (n) NHR1 (R-1 = CH3 or C2H5), led to the formation of the mono(4-nitrobenzyl)spiroc ... -
Phosphorus-nitrogen compounds. Part 36. Syntheses, Langmuir-Blodgett thin films and biological activities of spiro-bino-spiro trimeric phosphazenes
Asmafiliz, Nuran; Kilic, Zeynel; Civan, Mehmet; Avci, Orhan; Gonder, L. Yasemin; Acik, Leyla; Hokelek, Tuncer (Royal Soc Chemistry, 2016)The condensation reactions of hexachlorocyclotriphosphazene (N3P3Cl6, trimer) with the symmetric N2N2 or N2O2 donor type tetradentate bulky ligands (1-4) gave partly substituted spiro-bino-spiro (sbs) (5-8) trimeric ... -
Phosphorus-nitrogen compounds. Part 37. Syntheses and structural characterizations, biological activities of mono and bis(4-fluorobenzyl)spirocyclotetraphosphazenes
Elmas, Gamze; Okumus, Aytug; Sevinc, Pelin; Kilic, Zeynel; Acik, Leyla; Atalan, Mustafa; Hokelek, Tuncer (Royal Soc Chemistry, 2017)The Cl substitution reactions of octachlorocyclotetraphosphazene, N4P4Cl8, with one equimolar amount of (4-fluorobenzyl)diamines (1-3) affords mono(4-fluorobenzyl) spirocyclotetraphosphazenes (4-6) as minor products. ... -
Phosphorus-nitrogen compounds. part 38. Syntheses, characterizations, cytotoxic, antituberculosis and antimicrobial activities and DNA interactions of spirocyclotetraphosphazenes with bis-ferrocenyl pendant arms
Elmas, Gamze; Okumus, Aytug; Cemaloglu, Resit; Kilic, Zeynel; Celik, Suheyla Pinar; Acik, Leyla; Hokelek, Tuncer (Elsevier Science Sa, 2017)The reactions of N4P4Cl8 (1), with two equimolar amounts of N-(1-ferrocenylmethyl)-N-methyl-propylenediamine gave the monoferrocenyl-spiro (as a byproduct), bisferrocenyl-2-trans-6-dispiro (2) and bisferrocenyl-2-cis-6-dispiro ... -
Phosphorus-nitrogen compounds. Part 42. The comparative syntheses of 2-cis-4-ansa(N/O) and spiro(N/O) cyclotetraphosphazene derivatives: spectroscopic and crystallographic characterization, antituberculosis and cytotoxic activity studies
Binici, Arzu; Okumus, Aytug; Elmas, Gamze; Kilic, Zeynel; Ramazanoglu, Nagehan; Acik, Leyla; Hokelek, Tuncer (Royal Soc Chemistry, 2019)The reaction of N4P4Cl8 (1) with one equimolar amount of the sodium salt of an N/O donor-type bidentate ligand (2) afforded two kinds of derivatives, namely, mono-ferrocenyl-2-cis-4-dichloro-ansa- (2,4-ansa; 3) and ... -
Phosphorus-nitrogen compounds. Part 44. The syntheses of N,N-spiro bridged cyclotriphosphazene derivatives with (4-fluorobenzyl) pendant arms: Structural and stereogenic properties, DNA interactions, antimicrobial and cytotoxic activities
Ozturk, Ezel; Okumus, Aytug; Kilic, Zeynel; Kilic, Adem; Kayalak, Hande; Acik, Leyla; Hokelek, Tuncer (Elsevier Science Sa, 2019)Isopropylaminopentachlorocyclotriphosphazene, (N3P3Cl5(NHCHMe2) (1), containing a P-NH group in the alkyl-chain, gives the NN-spirobridged octachlorobiscyclotriphosphazene, [N3P3Cl4(NCHMe2)](2) (2), in the presence of NaH. ... -
Phosphorus-nitrogen compounds. Part 48. syntheses of the phosphazenium salts containing 2-pyridyl pendant arm: structural characterizations, thermal analysis, antimicrobial and cytotoxic activity studies
Elmas, Gamze; Okumus, Aytug; Kilic, Zeynel; Ozbeden, Pelin; Acik, Leyla; Tunali, Beste Cagdas; Turk, Mustafa (NATL INST SCIENCE COMMUNICATION-NISCAIR, 2020)The phosphazenium salts (protic ionic liquids, PILs/protic molten salts, PMOSs) (6a-6d and 7a) of the free phosphazene bases (4a-4d and 5a) have been prepared by the reactions of the corresponding cyclotriphosphazenes with ... -
Phosphorus-nitrogen compounds: Part 46. The reactions of N3P3Cl6 with bidentate and monodentate ligands: The syntheses, structural characterizations, antimicrobial and cytotoxic activities, and DNA interactions of (N/N)spirocyclotriphosphazenes with 4-chlorobenzyl pendant arm
Asmafiliz, Nuran; Berberoglu, Ipek; Ozgur, Mehtap; Kilic, Zeynel; Kayalak, Hande; Acik, Leyla; Hokelek, Tuncer (Elsevier Science Sa, 2019)In the present study, the partly and fully-substituted monospiro (4-6, 4a-6d), cis-dispiro (7-9), trans-dispiro (10-15) cyclotriphosphazenes were synthesized for the investigations of their chemical, stereogenic and ... -
Syntheses, spectroscopic and crystallographic characterizations of cis- and trans-dispirocyclic ferrocenylphosphazenes: molecular dockings, cytotoxic and antimicrobial activities
Tumer, Yasemin; Asmafiliz, Nuran; Zeyrek, C. Tugrul; Kilic, Zeynel; Acik, Leyla; Celik, S. Pinar; Hokelek, Tuncer (Royal Soc Chemistry, 2018)New cis-(4-6) and trans-dispirocyclic ferrocenylphosphazene derivatives (7-9) were obtained by reactions of hexachlorocyclotriphosphazene (N3P3Cl6) with N-alkyl-N-monoferrocenyldiamines of the formula FcCH(2)NH(CH2)(n)NHR ... -
Synthesis of Bis(2,2,3,3-tetrafluoro-1,4-butanedialkoxy)-2-trans-6-bis(4-fluorobenzyl)spirocyclotetraphosphazene: Structural Characterization, Biological Activity and DFT Studies
Elmas, Gamze; Kilic, Zeynel; Cosut, Bunyemin; Kesan, Gurkan; Acik, Leyla; Cam, Merve; Tunali, Beste Cagdas (SPRINGER/PLENUM PUBLISHERS, 2020)The Cl replacement reaction of octachlorocyclotetraphosphazene, N4P4Cl8 (1), with two equimolar amounts of N-(4-fluorobenzyl)-N'-methylpropane-1,3-diamine led to the formation of 4,4,8,8-tetrachloro-2-trans-6-bis-N-(4-fl ... -
Synthesis, Characterization And Dna Interaction Of Novel Platinum(Ii) Complexes Contaning Substituted Benzimidazole Ligands
Nzeyimana, Abdoul; Utku, Semra; Acik, Leyla; Keskin, Ayten Celebi (Editura Acad Romane, 2017)Eight novel Pt(II) complexes corresponding to the following general formula [PtCl2(L-1-L-4)(2)] (C1 -C4) and [PtI2((L1-L4))(2)] (C5-C8) in which 5(6)-chloro/or-methyl-2-H/or-methylbenzimidazole (L-1-L-4) played the key ...
