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The expression of GST and CYP isoenzymes in thyroid nodular hyperplasia and papillary thyroid cancer tissue: Correlation with clinical parameters
Oguztuzun, Serpil; Ergn, Duygu; Kilic, Murat; Bozer, Busra; Simsek, Gulcin Guler; Bulus, Hakan (Entomology & Applied Science Research Letters-Easletters, 2016)This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase (GST) pi(P), mu(M), theta(T), omega(O) and kappa(K) cytochrome P450 (CYP) A1, B1 and 2E1 isoenzymes in thyroid nodular ... -
Expressions of CYP and GST Isoenzymes in Human Gastric Tumor and Non-Tumor Tissues
Simsek, Gulcin G.; Oguztuzun, Serpil; Bozer, Busra; Kilic, Murat; Kocdogan, Arzu K.; Kaygin, Pinar; Bulus, Hakan (Akad Doktorlar Yayinevi, 2018)In this study we investigated the immunohistochemical staining characteristics of cytochrome P450 1A1 (CYP1A1), CYPB1, CYP2E1 and glutathione S-transferase P1 (GSTP1), GSTT1, GSTO1, GSTK1 isoenzymes in gastric tumor and ... -
Expressions of glutathione S-transferase alpha, mu, pi, and theta in the skin samples of patients with acne rosacea
Takci, Zennure; Bilgili, Serap Gunes; Kilic, Murat; Oguztuzun, Serpil; Bozer, Busra; Simsek, Gulcin Guler; Akbayrak, Atiye (WILEY, 2020)Background Data point to the importance of oxidative stress in rosacea. Glutathione S-transferases (GSTs) have substantial roles in a wide variety of oxidative stress-related conditions. Aim To evaluate the immunohistochemical ... -
Investigation of Glutathione S-Transferase Isoenzyme Protein Expression in Patients With Pterygium
Karadag, Remzi; Bayram, Nurettin; Oguztuzun, Serpil; Bozer, Busra; Bayramlar, Huseyin; Simsek, Gulcin Guler; Rapuano, Christopher J. (Lippincott Williams & Wilkins, 2016)Purpose: We investigated glutathione S-transferase (GST) enzymes in terms of their potential effects on the pathogenesis of pterygium. Methods: Twenty-six pterygium specimens and 15 normal conjunctival specimens of 15 ... -
An investigation of human beta-defensins and cathelicidin expression in patients with pterygium
Karadag, Remzi; Bayram, Nurettin; Oguztuzun, Serpil; Bayramlar, Huseyin; Bozer, Busra; Simsek, Gulcin; Rapuano, Christopher J. (Consel Brasil Oftalmologia, 2017)Purpose: To investigate human beta-defensins (HBDs) and cathelicidin LL-37 (LL-37) expressions in patients with pterygium. Methods: In this retrospective consecutive case series, 26 pterygium specimens and 15 normal ...