Yazar "Comu, Faruk Metin" için listeleme
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Dexmedetomidine protects against lipid peroxidation and erythrocyte deformability alterations in experimental hepatic ischemia reperfusion injury
Arslan, Mustafa; Comu, Faruk Metin; Kucuk, Aysegul; Ozturk, Levent; Yaylak, Faik (Taylor & Francis Ltd, 2012)Background: Hepatic ischemia-reperfusion injury is a common clinical problem in hepatic surgery and transplantation. Several cellular and tissue structural and functional alterations are observed in such injury. The aim ... -
Effect of dexmedetomidine on ischemia-reperfusion injury of liver and kidney tissues in experimental diabetes and hepatic ischemia-reperfusion injury induced rats
Sezen, Saban Cem; Isik, Berrin; Bilge, Mustafa; Arslan, Mustafa; Comu, Faruk Metin; Ozturk, Levent; Kavutcu, Mustafa (Anaesthesia Pain & Intensive Care, 2016)Background: Reperfusion following ischemia can lead to more injuries than ischemia itself especially in diabetic patients. The aim of this study was to evaluate the effect of dexmedetomidine on ischemia-reperfusion injury ... -
Effect of different doses of pregabalin on erythrocyte deformability in rats with lower limb ischemia reperfusion injury
Ozer, Abdullah; Comu, Faruk Metin; Demirtas, Huseyin; Kilic, Yigit; Mardin, Baris; Ozturk, Levent; Kucuk, Aysegul (Anaesthesia Pain & Intensive Care, 2017)Background & Objective: Acute ischemia reperfusion (IR) injury observed in the lower extremities occurs especially when a temporary cross-clamp is applied to the abdominal aorta during aortic surgery. Preoperative pregabalin ... -
The effect of different types of honey on healing infected wounds
Eroglu, Oguz; Deniz, Turgut; Kisa, Ucler; Comu, Faruk Metin; Kaygusuz, Sedat; Kocak, Orhan Murat (Ma Healthcare Ltd, 2018)Objective: To investigate the effects of treatments of 'mad honey', blossom honey and nitrofurazone on infected wound healing. Method: Male albino Wistar rats were randomly divided into four groups: 'mad honey' (MH), blossom ... -
The effect of levosinnendan on myocardial ischemia reperfusion injury in streptozotocin-induced diabetic rats
Kiraz, Hasan Ali; Poyraz, Fatih; Kip, Gulay; Erdem, Ozlem; Alkan, Metin; Arslan, Mustafa; Comu, Faruk Metin (Co-Action Publishing, 2015)Objective: Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio ... -
Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury
Comu, Faruk Metin; Kilic, Yigit; Ozer, Abdullah; Kirisci, Mehmet; Dursun, Ali Dogan; Tatar, Tolga; Arslan, Mustafa (Dove Medical Press Ltd, 2016)Background: Ischemia reperfusion injury (I/R) in hind limb is a frequent and important clinical phenomenon. Many structural and functional damages are observed in cells and tissues in these kinds of injuries. In this study, ... -
The Effect of Picroside-2 on Erythrocyte Deformability and Lipid Peroxidation in Streptozotocin-Induced Diabetic Rats subjected to Left Anterior Descending Artery-Ischemia reperfusion (conferenceObject)
Comu, Faruk Metin; Polat, Yucel; Ozer, Abdullah; Erer, Dilek; Kirisci, Mehmet; Dursun, Ali Dogan; Arslan, Mustafa (Wiley-Blackwell, 2015)… -
Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats
Arpaci, Hande; Comu, Faruk Metin; Kucuk, Aysegul; Kosem, Bahadir; Kartal, Seyfi; Sivgin, Volkan; Arslan, Mustafa (Dove Medical Press Ltd, 2016)Background: Change in blood supply is held responsible for anesthesia-related abnormal tissue and organ perfusion. Decreased erythrocyte deformability and increased aggregation may be detected after surgery performed under ... -
The Effects of Simvastatin on Ischemia Reperfusion Injury in an Experimental Colon Anastomosis Model
Akarsu, Mahmut; Saygun, Oral; Aydinuraz, Kuzey; Aydin, Oktay; Daphan, Cagatay Erden; Tanrikulu, Fatma Benli; Comu, Faruk Metin (Springer India, 2017)Anastomotic leakage is more frequently reported in colonic anastomoses. Ischemia reperfusion injury is one of the main reasons for anastomotic leakage. Simvastatin is known to prevent tissue damage induced by free oxygen ... -
Effects of the general anaesthetic agent, propofol, on erythrocyte deformability
Arslan, Mustafa; Comu, Faruk Metin; Isik, Berrin; Unal, Yusuf; Cekmen, Nedim; Kurtipek, Omer (Comenius Univ, 2010)Objectives: Propofol is an anesthetic agent frequently used for sedation and general anesthesia. The purpose of our study was to investigate the effect of propofol, a general anesthetic, on erythrocyte deformability in ... -
Gender-related alerations in erythrocyte mechanical activities under desflurane or sevoflurane anesthesia
Yerer, Muekerrem Betue; Aydogan, Sami; Comu, Faruk Metin (Ios Press, 2008)Alterations in erythrocyte mechanical activities under the influence of anesthesia have been observed and discussed among the responsible factors for the deterioration of tissue and organ perfusion related to anesthetic ... -
Investigation of Effects of Propofol and Vitamin C Administration on Hepatic and Renal Tissue in Diabetic Rats
Arslan, Mustafa; Bilge, Mustafa; Sezen, Saban Cem; Ozturk, Levent; Isik, Berrin; Comu, Faruk Metin; Yilmaz, Dervis (Gazi Univ, Fac Med, 2015)Obective: A close relationship between diabetic complications and lipid peroxidation is known. It was shown that in diabetic rat pharmacodynamics and pharmacokinetics of propofol was changed. We aim to investigate effects ... -
Protective effect of erdosteine on erythrocyte deformability in a rat model of lower limb ischemia/reperfusion injury
Ozer, Abdullah; Demirtas, Huseyin; Comu, Faruk Metin; Erer, Dilek; Kilic, Yigit; Mardin, Baris; Oktar, G. Levent (Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: The protective effect of erdosteine on local and distant organ injury due to ischemia/reperfusion has been well documented but its effect on erythrocyte deformability needs further investigation. Our aim ...
