Yazar "Denkbas, Emir Baki" için listeleme
-
Antisense oligonucleotide delivery to cancer cell lines for the treatment of different cancer types
Kilicay, Ebru; Erdal, Ebru; Hazer, Baki; Turk, Mustafa; Denkbas, Emir Baki (Taylor & Francis Ltd, 2016)Amphiphilic poly(3-hydroxylalkanoate) (PHA) copolymers find interesting applications in drug delivery. The aim of this study was to prepare nucleic acid adsorbed on (PHB-b-PEG-NH2) nanoparticle platform for gene delivery. ... -
Calcified and mechanically debilitated three-dimensional hydrogel environment induces hypertrophic trend in chondrocytes
Celik, Ekin; Bayram, Cem; Akcapinar, Rumeysa; Turk, Mustafa; Denkbas, Emir Baki (Sage Publications Ltd, 2016)Currently, the main focus on tissue engineering strategies is to mimic the extracellular matrix of the related tissues. Many studies accomplished to build tissue scaffolds to act as the natural surroundings of the specific ... -
Downregulation of ABCE1 via siRNA affects the sensitivity of A549 cells against chemotherapeutic agents
Kara, Goknur; Tuncer, Sema; Turk, Mustafa; Denkbas, Emir Baki (Humana Press Inc, 2015)ATP-binding cassette E1 (ABCE1) is involved in several biological functions in cancer cells such as tumor proliferation, antiapoptotic pathway and chemoresistance mechanism. This work aimed to investigate the alterations ... -
The effect of calcium chloride concentration on alginate/Fmoc-diphenylalanine hydrogel networks
Celik, Ekin; Bayram, Cem; Akcapinar, Rumeysaa; Turk, Mustafa; Denkbas, Emir Baki (Elsevier Science Bv, 2016)Peptide based hydrogels gained a vast interest in the tissue engineering studies thanks to great superiorities such as biocompatibility, supramolecular organization without any need of additional crosslinker, injectability ... -
Effects of ABCE1 Down-Regulation by RNAi on Chemosensitivity of Lung Cancer Cells
Kara, Goknur; Tuncer, Sema; Turk, Mustafa; Denkbas, Emir Baki (Int Inst Anticancer Research, 2014)… -
Novel layer-by-layer self-assembled peptide nanocarriers for siRNA delivery
Bozdogan, Betul; Akbal, Oznur; Celik, Ekin; Turk, Mustafa; Denkbas, Emir Baki (Royal Soc Chemistry, 2017)All complex and functional structures of nature consist of simple building blocks that are thermodynamically balanced and self-assembled at the molecular level. Production of functional bio-nanomaterials with molecular ... -
Preparation and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHX) based nanoparticles for targeted cancer therapy
Kilicay, Ebru; Demirbilek, Murat; Turk, Mustafa; Guven, Eylem; Hazer, Baki; Denkbas, Emir Baki (Elsevier Science Bv, 2011)Targeted drug delivery systems are one of the most promising alternatives for the cancer therapy. Rapid developments on nanomedicine facilitated the creation of novel nanotherapeutics by using different nanomaterials. ... -
Therapeutic potential of inhibiting ABCE1 and eRF3 genes via siRNA strategy using chitosan nanoparticles in breast cancer cells
Cengiz, Bagdat Burcu; Asik, Mehmet Dogan; Kara, Goknur; Turk, Mustafa; Denkbas, Emir Baki (Springer, 2015)In recent years, targeted cancer therapy strategies have begun to take the place of the conventional treatments. Inhibition of the specific genes, involved in cancer progress, via small interfering RNA (siRNA) has become ... -
Transscleral Delivery of Bevacizumab-Loaded Chitosan Nanoparticles
Ugurlu, Nagihan; Asik, Mehmet Dogan; Cakmak, Hasan Basri; Tuncer, Sema; Turk, Mustafa; Cagil, Nurullah; Denkbas, Emir Baki (Amer Scientific Publishers, 2019)Purpose: The aim of this study was to synthesize bevacizumab-loaded nanoparticles and evaluate their effects on the treatment of posterior segment diseases via subtenon injections. Methods: Bevacizumab-loaded chitosan ...
