Yazar "Karahan, Siyami" için listeleme
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Albino farelerde iyonlaştırıcı radyasyonun hepatosit morfolojisi ve prolifere hücre çekirdek antijeni (PCNA) ekspresyonu üzerindeki etkileri
Bu çalısmada, iyonlastırıcı radyasyonun albino farelerde hepatosit proliferasyon oranına etkisinin arastırılması amaçlandı. Normal ve iyonlastırıcı radyasyona maruz kalan albino fare hepatositlerindeki prolifere hücre ... -
Aljinat ile mikroenkapsülasyonu yapılan primer kondrositlerin hidrojel içi ve dışı kondrojenik potansiyelleri
Güçlü, Rumeysa (Kırıkkale Üniversitesi, 2014)Kıkırdak dokusunun tamir yeteneği oldukça sınırlıdır. Bu nedenle, osteoartritis gibi dejeneratif eklem hastalıklarında, hasarlı bölgelere taşıyıcı matriksler içinde kondrosit implantasyonu yapılması en güncel yaklaşımlar ... -
Ankyloglossia in Dogs: A Morphological and Immunohistochemical Study
Karahan, Siyami; Kul, Bengi Çınar (Wiley-Blackwell Publishing, Inc, 2009)Ankyloglossia is a congenital anomaly of the tongue that is usually characterized by a short and thick lingual frenulum. The genetic mutations such as in TBox genes and other foetal mechanism have still been under investigation ... -
Aromatase expression in the cerebellum of the dog infected with canine distemper virus
Yarım, Murat; Gülbahar, Mustafa Yavuz; Güvenç, Tolga; Karahan, Siyami; Harada, Nobuhiro; Kabak, Yonca Betil; Karayiğit, Mehmet Önder (Schluetersche Verlagsgesellschaft Mbh & Co Kg, 2010)Aromatase is the enzyme that catalyzes the biosynthesis of estrogens. It is implicated in neuroprotection. The present study investigated aromatase expression in the cerebellum of dogs infected with canine distemper virus ... -
Autologous stem cell-derived chondrocyte implantation with bio-targeted microspheres for the treatment of osteochondral defects
Bozkurt, Murat; Asik, Mehmet Dogan; Gursoy, Safa; Turk, Mustafa; Karahan, Siyami; Gumuskaya, Berrak; Dogan, Metin (Bmc, 2019)Background Chondral injury is a common problem around the world. Currently, there are several treatment strategies for these types of injuries. The possible complications and problems associated with conventional techniques ... -
Cerebellum progesterone concentration decreased in canine distemper virus infection
Yarim, Gül Fatma; Karahan, Siyami; Yarim, Murat (Elsevier Sci Ltd, 2007)Progesterone has neuroprotective effects including augmentation of myelination in the central and peripheral nervous system. This study was designed to determine if demyelinating lesions in the cerebellum resulting from ... -
Characterization and Evaluation of Triamcinolone, Raloxifene, and Their Dual-Loaded Microspheres as Prospective Local Treatment System in Rheumatic Rat Joints
Ocal, Yigit; Kurum, Baris; Karahan, Siyami; Tezcaner, Aysen; Ozen, Seza; Keskin, Dilek (Elsevier Science Inc, 2014)In this study, injectable microspheres were developed for the local treatment of joint degeneration in rheumatoid arthritis (RA). Microspheres loaded with triamcinolone (TA), a corticosteroid drug, and/or raloxifene (Ral), ... -
Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds
Turk, Mustafa; Karahan, Siyami; Cinar, Miyase; Kucuk, Sebnem; Dincel, Gungor Cagdas (Informa Healthcare, 2013)Bovine chondrocytes were seeded into scaffolds of a high molecular weight chitosan and alginate with a pore size of 50-350 mu m with or without catechin. In polymerase chain reaction (PCR), unlike type II, collagen type I ... -
Choroid epithelial cells: Source cerebrospinal fluid progesterone in sheep?
Karahan, Siyami; Yarım, Gül F.; Yarım, Murat (2007)The present study was conducted to immunolocalize 3?-hydroxysteroid dehydrogenase (3?-HSD), an enzyme metabolizing pregnenolone to progesterone in the choroid plexus of the lateral ventricle in sheep, as well as to measure ... -
Determination of antioxidants in bovine oviduct epithelial cell culture isolated at different periods of the estrous cycle
Kurum, Aytul; Karahan, Siyami; Kocamis, Hakan; Cinar, Miyase; Ergun, Emel (Scientific Technical Research Council Turkey-Tubitak, 2019)Oxidative stress interferes with oviduct functions including oocyte maturation, capacitation, fertilization, and embryo and gamete transport. This study aimed to determine activity of the antioxidants glutathione peroxidase ... -
Effects Of Ankaferd Blood Stopper-Reinforced Platelet-Rich Fibrin Membrane On Guided Tissue Regeneration In Experimental Bone Defects
Özer, Taha; Aktaş, Alper; Karahan, Siyami (2019)Background and Aim: To evaluate the effects of AnkaferdBlood Stopper added platelet-rich fibrin administered incranial bone defects created in rabbits via histomorphometricassessment.Materials and Method: Four circular 5 ... -
Effects of Local Low-Dose Alendronate Injections Into the Distraction Gap on New Bone Formation and Distraction Rate on Distraction Osteogenesis
Alp, Yunus Emre; Taskaldiran, Alper; Onder, Mustafa Ercument; Karahan, Siyami; Kocyigit, Ismail Doruk; Atil, Fethi; Tekin, Umut (Lippincott Williams & Wilkins, 2017)Bisphosphonates that constrain bone resorption have a direct effect on osteoclast function. In this experimental study, the effects of low-dose local alendronate injections on the distraction gap (DG) in rabbit mandible ... -
Effects of water quality and fish size on toxicity of methiocarb, a carbamate pesticide, to rainbow trout
Altınok, İlhan; Çapkın, Erol; Karahan, Siyami; Boran, Muhammet (Elsevier, 2006)The acute toxicity of methiocarb in juvenile rainbow trout (Oncorhynchus mykiss, 3.25 +/- 0.79 g) was evaluated in glass aquaria under static conditions. Nominal concentrations of methiocarb in the toxicity test ranged ... -
Evaluation of melamine and cyanuric acid cytotoxicity: an in vitro study on L929 fibroblasts and CHO cell line
Melekoglu, Abdullah; Ekici, Husamettin; Arat, Esra; Karahan, Siyami (ANKARA UNIV PRESS, 2020)Melamine and its metabolites pose health concern as they are used in various industrial products including feed and drugs. There are a limited number of studies on melamine and cyanuric acid cytotoxicity and cellular damage ... -
Fabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblasts
Turk, Mustafa; Tamer, Ugur; Alver, Erol; Ciftci, Hakan; Metin, Aysegul U.; Karahan, Siyami (Taylor & Francis Ltd, 2013)The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929-fibroblasts. L929-fibroblasts were seeded ... -
Histomorphometric examination of the pineal gland in foals and adult horses
Bolat, Durmus; Kurum, Aytul; Bahar, Sadullah; Karahan, Siyami (Ankara Univ Press, 2018)This study was conducted to evaluate the pineal glands of the foal and adult horses with histomorphometry. The pineal glands were sectioned at a thickness of 40 mu m and stained with AgNOR for stereological analyses. The ... -
Immunohistochemical expression of anti-oxidants in bovine oviduct epithelial cells of estral and luteal phases
Summary: The present study aimed to evaluate immunohistochemical distributions of anti-oxidative enzymes Cu Zn-Superoxide dismutase (SOD-1), catalase, and Glutation peroxidase-1 (GPX1) in the bovine oviduct epithelial cells ... -
Immunohistochemical investigation of CD14 in experimental rabbit pneumonic pasteurellosis
Yarım, Murat; Karahan, Siyami; Kabakcı, N. (Ecole Nationale Veterinaire Toulouse, 2005)The present study investigated the immunolocalization of CD 14 and the bacterial antigen of Pasteurella multocida serotype A :3 in normal and pneumonic rabbit lungs. To induce pneumonia, P. multocida serotype A :3 (4 x ... -
Immunolocalization of 3β-hydroxysteroid dehydrogenase in normal and hyperplastic ram prostates
Yarım, Murat; Karahan, Siyami; Kabakcı, Nalan; Atmaca, Tarık (Elsevier Science Inc, 2006)The enzyme 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) is essential in the synthesis of all steroids by cleaving dehydroepiandrosterone to androstenedione. In the present study, 3 beta-HSD immunoreactivity was ... -
In-vivo efficacy of toltrazuril on experimentally induced Toxoplasma gondii tissue cysts in lambs: A novel strategy for prevention of human exposure to meat-borne toxoplasmosis
Kul, Oğuz; Yıldız, Kader; Öcal, Naci; Freyre, Alvaro; Deniz, Abdulkerim; Karahan, Siyami; Terzi, Osman Safa (Elsevier Sci Ltd, 2013)The aim of the present study was to investigate in vivo efficacy of toltrazuril on Toxoplasma gondii tissue cysts following induction of chronic toxoplasmosis in 4-week-old lambs (n = 27) by inoculation of 1 x 105 T. gondii ...