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Effects of Intracisternal Dexmedetomidine on Cerebral Neuronal Cells in Rat: A Preliminary Study
Kose, Emine Arzu; Bakar, Bulent; Kasimcan, Omur; Atilla, Pergin; Kilinc, Kamer; Muftuoglu, Sevda; Apan, Alpaslan (Turkish Neurosurgical Soc, 2013)AIM:The aim was to investigate whether dexmedetomidine had a toxic effect on cerebral neurons when it was administered centrally into the cerebrospinal fluid by the intracisternal route. MATERIAL and METHODS: Eighteen rats ... -
Effects of low-dose methotrexate in spinal cord injury in rats
Bakar, Bulent; Kose, Emine Arzu; Kupana Ayva, Sebnem; Sarkarati, Bahram; Kasimcan, Mustafa Omur; Kilinc, Kamer (Turkish Assoc Trauma Emergency Surgery, 2013)BACKGROUND This study was designed to evaluate the possible protective effects of low-dose methotrexate in the spinal cord injury (SCI) in rats. METHODS Thirty-seven Wistar albino rats were used in the present study. Except ... -
Evaluation of the neurotoxicity of DMSO infused into the carotid artery of rat
Bakar, Bulent; Kose, Emine Arzu; Sonal, Sevilay; Alhan, Aslihan; Kilinc, Kamer; Keskil, Ismail Semih (Elsevier Sci Ltd, 2012)Introduction: Despite the explanations put forth in many studies regarding histopathological evidence of the inflammatory stage related with the infusion of dimethyl sulfoxide (DMSO) in the vessel wall and its lumen, there ...