Yazar "Korkusuz, Petek" için listeleme
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A 6-month in vivo study of polymer/mesenchymal stem cell constructs for cranial defects
Aydin, Halil Murat; Korkusuz, Petek; Vargel, Ibrahim; Kilic, Emine; Guzel, Elif; Cavusoglu, Tarik; Piskin, Erhan (Sage Publications Ltd, 2011)Two biodegradable polymers, poly(L-lactide) and poly(epsilon-caprolactone) were blended (50/50) and used to produce polymeric scaffolds by the dual porogen approach using a salt leaching technique to create pores within ... -
Cranial bone regeneration via BMP-2 encoding mesenchymal stem cells
Vural, Altugan Cahit; Odabas, Sedat; Korkusuz, Petek; Saglam, Atiye Seda Yar; Bilgic, Elif; Cavusoglu, Tarik; Vargel, Ibrahim (Taylor & Francis Ltd, 2017)Cranial bone repair and regeneration via tissue engineering principles has attracted a great deal of interest from researchers during last decade. Here, within this study, 6mm critical-sized bone defect regeneration via ... -
Effect of Locally Administered Alendronate on Onlay Grafts
Tekin, Umut; Ozgul, Ozkan; Tuz, Hakan; Korkusuz, Petek; Kocyigit, Ismail Doruk; Atil, Fethi; Onder, M. Ercument (Amer Scientific Publishers, 2017)Objective: The present study compared the effects of local alendronate application on the osteogenesis of autogenous and xenogenous onlay grafts implanted in rabbit mandibles. Material and Methods: 28 New Zealand rabbits ... -
Effect of Use of Slow Release of Bone Morphogenetic Protein-2 and Transforming Growth Factor-Beta-2 in a Chitosan Gel Matrix on Cranial Bone Graft Survival in Experimental Cranial Critical Size Defect Model
Canter, Halil Ibrahim; Vargel, Ibrahim; Korkusuz, Petek; Oner, Filiz; Gungorduk, Dilsad B.; Cil, Barbaros; Erk, Yucel (Lippincott Williams & Wilkins, 2010)Bone grafts, used for providing structural integrity of cranial vault remodeling, could not always integrate with the remaining bone structures. All efforts are focused on increasing incorporation of the applied bone grafts. ... -
Effects of alendronate on rate of distraction in rabbit mandibles
Tekin, Umut; Tuz, Hakan H.; Onder, Ercument; Ozkaynak, Ozkan; Korkusuz, Petek (W B Saunders Co-Elsevier Inc, 2008)Purpose: Bisphosphonates are used for inhibiting bone resorption in several diseases. In this experimental study, the effects of alendronate on the mandibular distraction gap in rabbits at 2 different rates were evaluated. ... -
The Effects of Beta-blockers on Endothelial Nitric Oxide Synthase Immunoreactivity in the Rat Corpus Cavernosum
Dogru, Mehmet Tolga; Aydos, Tolga Resat; Aktuna, Zuhal; Korkusuz, Petek; Zeybek, Dilara; Gorgu, Nart; Basar, Mehmet Murad (Elsevier Science Inc, 2010)OBJECTIVES To explain the mechanism of the effects of beta-blockers on endothelial dysfunction and release of nitric oxide from the endothelium. METHODS A total of 72 Sprague-Dawley rats were divided into 9 different groups ... -
Focused RF hyperthermia using magnetic fluids
Tasci, T. Onur; Vargel, İbrahim; Arat, Anıl; Güzel, Elif; Korkusuz, Petek; Atalar, Ergin (Wiley, 2009)Heat therapies such as hyperthermia and thermoablation are very promising approaches in the treatment of cancer. Compared with available hyperthermia modalities, magnetic fluid hyperthermia (MFH) yields better results in ... -
Stem cell suspension injected HEMA-lactate-dextran cryogels for regeneration of critical sized bone defects
Bolgen, Nimet; Korkusuz, Petek; Vargel, Ibrahim; Kilic, Emine; Guzel, Elif; Cavusoglu, Tarik; Piskin, Erhan (Taylor & Francis Ltd, 2014)HEMA-Lactate-Dextran cryogel scaffolds were produced by cryogelation. Mesencyhmal stem cells (MSC) were isolated from rat bone marrow. Critical sized cranial bone defects were created in rat cranium. Stem cells were injected ... -
Stem cells combined 3D electrospun nanofibrous and macrochannelled matrices: a preliminary approach in repair of rat cranial bones
Isoglu, Ismail Alper; Bolgen, Nimet; Korkusuz, Petek; Vargel, Ibrahim; Celik, Hakan Hamdi; Kilic, Emine; Piskin, Erhan (Taylor & Francis Ltd, 2019)Repair of cranial bone defects is an important problem in the clinical area. The use of scaffolds combined with stem cells has become a focus in the reconstruction of critical-sized bone defects. Electrospinning became a ... -
Tissue responses to novel tissue engineering biodegradable cryogel scaffolds: An animal model
Bolgen, Nimet; Vargel, Ibrahim; Korkusuz, Petek; Guzel, Elif; Plieva, Fatima; Galaev, Igor; Piskin, Erhan (Wiley, 2009)Biodegradable macroporous cryogels with highly open and interconnected pore structures were produced from dextran modified with oligo L-lactide bearing hydroxyethylmethacrylate (HEMA) end groups in moderately frozen ...
