Yazar "Ozkanli, Seyma" için listeleme
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Alteration of tissue expression of human beta defensin-1 and human beta defensin-2 in psoriasis vulgaris following phototherapy
Uzuncakmak, Tugba Kevser; Karadag, Ayse Serap; Ozkanli, Seyma; Akbulak, Ozge; Ozlu, Emin; Akdeniz, Necmettin; Oguztuzun, Serpil (Taylor & Francis Ltd, 2020)We compared the expression profiles of antimicrobial peptides (AMPs) in psoriatic skin before and after narrow band ultraviolet B (nb-UVB) phototherapy and compared the levels to healthy controls. We studied 15 male and ... -
Caspase-3, p53 and Bcl-2 expression in basal cell carcinoma of the eyelid
Koyun, Efe; Karadag, Remzi; Ozkanli, Seyma; Ogurtuzun, Serpil; Kocdogan, Arzu Kaya; Ozsoy, Isilay (TERMEDIA PUBLISHING HOUSE LTD, 2020)Introduction: Eyelid tumours mostly originated from skin and its appendeges. External carcinogens like UV radiation causes cell damages in the eyelid skin and contributes to carcinogenesis. Apoptosis is a very important ... -
Comparison of the tissue expressions of glutathione S transferase isoenzymes among patients with morphea and healthy controls: A preliminary study
Uzuncakmak, Tugba Kevser; Koska, Mahmut Can; Ozkanli, Seyma; Kocdogan, Arzu Kaya; Oguztuzun, Serpil; Karadag, Ayse Serap; Akdeniz, Necmettin (WILEY, 2020)Morphea is an inflammatory connective tissue disorder, which is characterized by sclerosis in skin and subcutaneous tissues with a chronic progress. The oxidative stress in pathogenesis of sclerosing diseases was proposed ... -
Comparison of TLR-2, TLR-4, and antimicrobial peptide levels in different lesions of acne vulgaris
Ozlu, Emin; Karadag, Ayse Serap; Ozkanli, Seyma; Oguztuzun, Serpil; Kilic, Murat; Zemheri, Ebru; Akdeniz, Necmettin (Taylor & Francis Ltd, 2016)Context: Recent studies have shown that tolls like receptors (TLRs) and antimicrobial peptides (hBD-1, cathelicidin) play an important role in the pathogenesis of acne vulgaris (AV).Objective: To evaluate and report the ... -
Evaluation of oxidative stress via protein expression of glutathione S-transferase and cytochrome p450 (CYP450) soenzymes in psoriasis vulgaris patients treated with methotrexate
Akbulak, Ozge; Karadag, Ayse Serap; Akdeniz, Necmettin; Ozkanli, Seyma; Ozlu, Emin; Zemheri, Ebru; Oguztuzun, Serpil (Taylor & Francis Ltd, 2018)Introduction: Oxidative stress is the imbalance between oxidant-antioxidant systems and may play a major role in the psoriasis pathogenesis. Cytochrome (CYP) is a family of enzymes that are responsible for the metabolism ... -
The investigation of antimicrobial peptides expression and its related interaction with methotrexate treatment in patients with psoriasis vulgaris
Ozlu, Emin; Karadag, Ayse Serap; Ozkanli, Seyma; Oguztuzun, Serpil; Akbulak, Ozge; Uzuncakmak, Tugba Kevser; Akdeniz, Necmettin (Taylor & Francis Ltd, 2017)Background: Psoriasis is a chronic, inflammatory and immune-mediated disease. Recently, the role of antimicrobial peptides (AMPs) such as human beta defensins (hBDs) in the pathogenesis of psoriasis has been investigated. ... -
An investigation of cytochrome p450 (CYP) and glutathione S-transferase (GST) isoenzyme protein expression and related interactions with phototherapy in patients with psoriasis vulgaris
Karadag, Ayse S.; Uzuncakmak, Tugba K.; Ozkanli, Seyma; Oguztuzun, Serpil; Moran, Busra; Akbulak, Ozge; Akdeniz, Necmettin (Wiley-Blackwell, 2017)Oxidative stress may play an important role in the pathogenesis of psoriasis. Glutathione S-transferases (GSTs) make up a group of antioxidant enzymes. Cytochrome p450 (CYP) enzymes can influence oxidation and reduction ...