Yazar "Ozpolat, Bulent" için listeleme
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MicroRNA 603 acts as a tumor suppressor and inhibits triplenegative breast cancer tumorigenesis by targeting elongation factor 2 kinase
Bayraktar, Recep; Pichler, Martin; Kanlikilicer, Pinar; Ivan, Cristina; Bayraktar, Emine; Kahraman, Nermin; Ozpolat, Bulent (Impact Journals Llc, 2017)Triple negative breast cancer (TNBC) is an aggressive type of breast cancer characterized by the absence of defined molecular targets, including estrogen receptor (ER), progesterone receptor (PR), human epidermal growth ... -
Modified gold-based siRNA nanotherapeutics for targeted therapy of triple-negative breast cancer
Shahbazi, Reza; Asik, Elif; Kahraman, Nermin; Turk, Mustafa; Ozpolat, Bulent; Ulubayram, Kezban (Future Medicine Ltd, 2017)Aim: In this study, we aimed to therapeutically target eukaryotic elongation factor 2 kinase (eEF-2K) in an in vivo triple-negative breast cancer (TNBC) tumor model. Materials & methods: We synthesized a highly monodisperse ...