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Association of CYP3A5 Expression and Vincristine Neurotoxicity in Pediatric Malignancies in Turkish Population
Kayilioglu, Hulya; Kocak, Ulker; Karaer, Derya Kan; Percin, Emriye F.; Sal, Ertan; Tekkesin, Funda; Gursel, Turkiz (Lippincott Williams & Wilkins, 2017)Vincristine is a widely used chemotherapeutic agent in the treatment of childhood malignancies. Neuropathy is the most common adverse effect. CYP3A4 and CYP3A5 enzymes of cytochrome p450 enzyme system are responsible in ...
