Yazar "Simsek, Gulcin Guler" için listeleme
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Effects of Different Doses of Systemic Isotretinoin on Eyes: A Histopathological and Immunohistochemical Study in Rats
Karadag, Remzi; Karadag, Ayse Serap; Ozlu, Emin; Oguztuzun, Serpil; Simsek, Gulcin Guler; Esmer, Oktay; Bilgili, Serap Gunes (Lippincott Williams & Wilkins, 2020)Purpose: To evaluate ocular side effects associated with systemic isotretinoin histopathologically. Methods: In this multicenter study, a total of 15 male and 15 female rats were randomly divided into 3 equal groups according ... -
The expression of GST and CYP isoenzymes in thyroid nodular hyperplasia and papillary thyroid cancer tissue: Correlation with clinical parameters
Oguztuzun, Serpil; Ergn, Duygu; Kilic, Murat; Bozer, Busra; Simsek, Gulcin Guler; Bulus, Hakan (Entomology & Applied Science Research Letters-Easletters, 2016)This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase (GST) pi(P), mu(M), theta(T), omega(O) and kappa(K) cytochrome P450 (CYP) A1, B1 and 2E1 isoenzymes in thyroid nodular ... -
Expression of Sigma-Class Glutathione-S-Transferase in Fetal and Pediatric Filum Terminale Samples: A Comparative Study
Kural, Cahit; Ogurtuzun, Serpil; Simsek, Gulcin Guler; Guresci, Servet; Kaygin, Pinar; Yasar, Soner; Izci, Yusuf (Mdpi, 2019)Background and objectives: The pathophysiology of tethered cord syndrome (TCS) in children is not well elucidated. An inelastic filum terminale (FT) is the main factor underlying the stretching of the spinal cord in TCS. ... -
Expressions of glutathione S-transferase alpha, mu, pi, and theta in the skin samples of patients with acne rosacea
Takci, Zennure; Bilgili, Serap Gunes; Kilic, Murat; Oguztuzun, Serpil; Bozer, Busra; Simsek, Gulcin Guler; Akbayrak, Atiye (WILEY, 2020)Background Data point to the importance of oxidative stress in rosacea. Glutathione S-transferases (GSTs) have substantial roles in a wide variety of oxidative stress-related conditions. Aim To evaluate the immunohistochemical ... -
Glutathione S-Transferases and Cytochrome P450 Enzyme Expression in Patients with Intracranial Tumors: Preliminary Report of 55 Patients
Kural, Cahit; Kocdogan, Arzu Kaya; Simsek, Gulcin Guler; Oguztuzun, Serpil; Kaygin, Pinar; Yilmaz, Irmak; Izci, Yusuf (Karger, 2019)Objective: Intracranial tumors are one of the most frightening and difficult-to-treat tumor types. In addition to surgery, protocols such as chemotherapy and radiotherapy also take place in the treatment. Glutathione ... -
Investigation of Glutathione S-Transferase Isoenzyme Protein Expression in Patients With Pterygium
Karadag, Remzi; Bayram, Nurettin; Oguztuzun, Serpil; Bozer, Busra; Bayramlar, Huseyin; Simsek, Gulcin Guler; Rapuano, Christopher J. (Lippincott Williams & Wilkins, 2016)Purpose: We investigated glutathione S-transferase (GST) enzymes in terms of their potential effects on the pathogenesis of pterygium. Methods: Twenty-six pterygium specimens and 15 normal conjunctival specimens of 15 ...