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Antileukotrienes in Upper Airway Inflammatory Diseases

Cingi, Cemal; Muluk, Nuray Bayar; Ipci, Kagan; Sahin, Ethem (Current Medicine Group, 2015)

Leukotrienes (LTs) are a family of inflammatory mediators including LTA(4), LTB4, LTC4, LTD4, and LTE4. By competitive binding to the cysteinyl LT1 (CysLT(1)) receptor, LT receptor antagonist drugs, such as montelukast, ...

Aspirin-exacerbated respiratory disease and current treatment modalities

Sakalar, Emine Guven; Muluk, Nuray Bayar; Kar, Murat; Cingi, Cemal (Springer, 2017)

Aspirin-exacerbated respiratory disease (AERD) refers to the combination of asthma, chronic rhinosinusitis with nasal polyposis, and acute upper and lower respiratory tract reactions to the ingestion of aspirin (acetylsalicylic ...