• The Effects of HES 130/0.4 Application on Erythrocyte Deformability in Ureteral Obstructed Rats 

  Güneş, Işın; Küçük, Ayşegül; Çomu, Faruk Metin; Şıvgın, Volkan; Alkan, Metin; Arslan, Mustafa; Ünal, Yusuf (2018)

  Amaç: Plazma genişleticilerinin uygulanması, önemli cerrahi, hemorajik şok ve travmayı içeren çeşitli klinik koşullardaki kritik hastaları yönetmek için çok önemlidir. Bununla birlikte, hidroksietil nişastanın (HES) eritrosit ...

• Effect of Levosimendan and Nigella Sativa on Erythrocyte Deformability During Myocardial Ischaemia-Reperfusion Injury in Rats 

  Özer, Abdullah; Çomu, Faruk Metin; Küçük, Ayşegül; Kılıç, Yiğit; Mardin, Barış; Alkan, Metin; Oktar, Gürsel Levent (2018)

  Amaç: İskemi-reperfüzyon (İR) hasarı, doku iskemisi sonucu gerçekleşen bir olaylar zinciridir. Hücresel hasarı takiben reperfüzyon, aktif bir inflamatuar yanıta neden olur. Eritrosit deformabilitesi ve plazma viskozitesi ...

• Investigation of the Effects of Sevoflurane and Desflurane on Erythrocyte Deformability in Transient Hyperglycemia 

  Kalaycı, Dilek; Arpacı, Ayşe Hande; Çomu, Faruk Metin; Güneş, Işın; Beşkardeş, Elif; Kurtipek, Ömer; Arslan, Mustafa (2018)

  Aim: Micro and macrovascular complications due to long-term hyperglycemia are associated with increased mortality and morbidity. Erythrocytes exposed to hyperglycemia for a long time may cause morphological changes in ...

• The Effect of Picroside-2 on Erythrocyte Deformability and Lipid Peroxidation in StreptozotocinInduced Diabetic Rats Subjected to Left Anterior Descending Artery-Ischaemia Reperfusion 

  Çomu, Faruk Metin; Polat, Yücel; Özer, Abdullah; Erer, Dilek; Kirişçi, Mehmet; Dursun, Ali Doğan; Tatar, Tolga (2017)

  Aim: Diabetes mellitus (DM) is a chronic metabolic disorder principally characterized by an elevation in oxidative stress levels. Ischaemia-reperfusion (IR) injury starts a cascade of events that lead to tissue ischaemia ...

• Trpv2 Polymorphisms Change The Risk Of Type 2 Diabetes - Hashimoto Thyroiditis Comorbidity 

  Arikan, F. Bulut; Ozdemir, F. A.; Sen, D.; Erdem, S.; Yorubulut, S.; Dogan, H.; Keskin, L. (EDITURA ACAD ROMANE, 2020)

  Context. Thyroid disorders are common in diabetics and related to severe diabetic complications. TRPV2 ion channels have crucial functions in insulin secretion and glucose metabolism which have an important role in the ...

• Effects of N-Acetylcysteine and N-Acetylcysteine Amide on Erythrocyte Deformability and Oxidative Stress in a Rat Model of Lower Extremity Ischemia-Reperfusion Injury 

  Erol, Gokhan; Kartal, Hakan; Comu, Faruk M.; Cetin, Erdem; Demirdas, Ertan; Sicim, Huseyin; Unal, Celal S. (HINDAWI LTD, 2020)

  N-acetylcysteine (NAC) is an antioxidant which works as a free radical scavenger and antiapoptotic agent. N-acetylcysteine-amide (NACA) is a modified form of NAC containing an amide group instead of a carboxyl group of ...

• Effect of Fullerenol C60 on Erythrocyte Deformability During Ischaemia-Reperfusion Injury of Lower Extremity in Diabetic Rats 

  Kip, Gülay; Kartal, Hakan; Çomu, Faruk Metin; Polat, Yücel; Arslan, Mustafa; Küçük, Ayşegül (Gazi Univ, Fac Med, 2019)

  Background: Fullerenol, a water-soluble C60-fullerene derivative synthesized by Chiang et al, has been demonstrated to be able to scavenge free radicals in vitro and in vivo. Although its protective effects have been already ...

• Protective effect of erdosteine on erythrocyte deformability in a rat model of lower limb ischemia/reperfusion injury 

  Ozer, Abdullah; Demirtas, Huseyin; Comu, Faruk Metin; Erer, Dilek; Kilic, Yigit; Mardin, Baris; Oktar, G. Levent (Tubitak Scientific & Technical Research Council Turkey, 2018)

  Background/aim: The protective effect of erdosteine on local and distant organ injury due to ischemia/reperfusion has been well documented but its effect on erythrocyte deformability needs further investigation. Our aim ...

• Investigation of the effects of thymoquinone on erythrocyte deformability in sepsis treatment which created by cecal perforation in rat 

  Bostanci, H.; Dikmen, K.; Comu, F. M.; Arslan, M.; Kucuk, A. (Comenius Univ, 2018)

  AIM: We aimed to study the effects of thymoquinone on erythrocyte deformability in an experimental model of sepsis given before or after the initiation of the sepsis model. METHOD: The animals were grouped as (n = 6) ...

• Assessment of the effects of levosimendan and thymoquinone on lung injury after myocardial ischemia reperfusion in rats 

  Sezen, Saban Cem; Kucuk, Aysegul; Ozer, Abdullah; Kilic, Yigit; Mardin, Baris; Alkan, Metin; Tosun, Murat (Dove Medical Press Ltd, 2018)

  Aim: The aim of this study was to investigate the effects of levosimendan and thymoquinone (TQ) on lung injury after myocardial ischemia/reperfusion (I/R). Materials and methods: Twenty-four Wistar albino rats were included ...

• Effect of cerium oxide on erythrocyte deformability in rat lower extremity ischemia reperfusion injury 

  Tatar, T.; Polat, Y.; Comu, F. M.; Kartal, H.; Arslan, M.; Kucuk, A. (Comenius Univ, 2018)

  BACKGROUND: Cerium oxide is the oxide form of cerium, which has protective effects in ischemia reperfusion (I/R) injury. The purpose of our study was to look into the effects of this rare-earth metal on erythrocyte ...

• Vitamin A And E Levels In Patients With Chronic Kidney Disease 

  Aksoy, Aziz; Gozel, Nevzat; Bulut-Arikan, Funda; Kucuksu, Mehmet; Ozdemir, Fethi Ahmet (Parlar Scientific Publications (P S P), 2018)

  Chronic kidney disease (CKD) is a disease that manifests itself with abnormalities in kidney structure or function. Inflammation and oxidative stress increase in kidney disease in parallel with the advancement of the ...

• Effects of dexmedetomidine and thymoquinone on erythrocyte deformability in lower limb ischemia reperfusion injury in streptozotocin-induced diabetic rats 

  Ozer, A.; Comu, F. M.; Kucuk, A.; Kilic, Y.; Alkan, M.; Oktar, L.; Ozturk, L. (Comenius Univ, 2018)

  OBJECTIVE: In this study we aimed to evaluate the effect of dexmedetomidine and thymoquinone on erythrocyte deformability in lower limb ischaemia-reperfusion (IR) injury in streptozotocin-induced diabetic rats. MATERIAL ...

• The effect of different types of honey on healing infected wounds 

  Eroglu, Oguz; Deniz, Turgut; Kisa, Ucler; Comu, Faruk Metin; Kaygusuz, Sedat; Kocak, Orhan Murat (Ma Healthcare Ltd, 2018)

  Objective: To investigate the effects of treatments of 'mad honey', blossom honey and nitrofurazone on infected wound healing. Method: Male albino Wistar rats were randomly divided into four groups: 'mad honey' (MH), blossom ...

• Effect of apelin-13 on erythrocyte deformability during ischaemia-reperfusion injury of heart in diabetic rats 

  Kartal, H.; Comu, F. M.; Kucuk, A.; Polat, Y.; Dursun, A. D.; Arslan, M. (Comenius Univ, 2017)

  OBJECTIVES: Erythrocyte deformability and plasma viscosity are of crucial importance for the perfusion of tissues and organs. The aim of this study was to evaluate the effect of apelin-13 on erythrocyte deformability during ...

• Interleukin-6 and hepcidin expression changes in cardiac tissue of long-term trained and untrained rats after exhaustive exercise 

  Sarikaya, Badegul; Dursun, Ali Dogan; Taylan Deveden, Elcin Yagmur; Pinar, Lamia (Tubitak Scientific & Technical Research Council Turkey, 2017)

  Background/aim: Exercise benefits the cardiovascular system, but strenuous exercise can cause cardiac damage and induce cytokine production, particularly that of interleukin-6 (IL-6). Hepcidin, which is primarily regulated ...

• The Effects the Rat Luteal Cells on Islet Cells Revascularization and Immune Response 

  Boyuk, Gulbahar; Yigit, A. Arzu (Wiley, 2017)

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• The Effects of Simvastatin on Ischemia Reperfusion Injury in an Experimental Colon Anastomosis Model 

  Akarsu, Mahmut; Saygun, Oral; Aydinuraz, Kuzey; Aydin, Oktay; Daphan, Cagatay Erden; Tanrikulu, Fatma Benli; Comu, Faruk Metin (Springer India, 2017)

  Anastomotic leakage is more frequently reported in colonic anastomoses. Ischemia reperfusion injury is one of the main reasons for anastomotic leakage. Simvastatin is known to prevent tissue damage induced by free oxygen ...

• Association of physical activity and obesity status for individuals between the ages of 18-30 via bioelectrical impedance analysis device and metabolic holter measurements 

  Aksoy, Aziz; Selen, Halime; Ozdemir, Fethi Ahmet; Arikan, Funda Bulut (Mattioli 1885, 2017)

  Obesity, according to its simplest definition, is excessive accumulation of fat in the body. Obesity is a health problem that is observed commonly in almost all societies and it is starting to become a global epidemic. In ...

• Vitamin C ameliorates high dose Dexmedetomidine induced liver injury 

  Arslan, M.; Sezen, S. C.; Turgut, H. C.; Kocabiyik, M.; Arpaci, H.; Comu, F. M.; Kavutcu, M. (Comenius Univ, 2016)

  BACKGROUND: We investigated whether vitamin C has protective effects on rat liver tissue treated with different dexmedetomidine doses. MATERIAL AND METHODS: Thirty five wistar albino rats were randomly divided into 5 groups ...

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