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Systemic toxoplasmosis in a kangaroo (Macropus sp.)
(Ankara Univ Press, 2011)This paper describes systemic toxoplasmosis in a brush kangaroo died after diagnosed with chronic diarrhoea in a local zoo. Macroscopically, widespread subcutaneous petechial haemorrhagies, 100 ml sero-sanguineous fluid ... -
Clinicopathologic diagnosis of cutaneous toxoplasmosis in an Angora cat
(Schluetersche Verlagsgesellschaft Mbh & Co Kg, 2011)This report deals with a case of cutaneous toxoplasmosis in a 2 year-old female Angora cat. Cutaneous lesions were characterized by prescapular ulcers and hyperemic nodules in the skin of the inguinal and dorsosacral ... -
A Cannabinoid Ligand, Anandamide, Exacerbates Endotoxin-Induced Uveitis in Rabbits
(Mary Ann Liebert Inc, 2011)Purpose: This study aimed to investigate the effects of anandamide or arachidonylethanolamide (AEA), an endogenous cannabinoid receptor agonist, on intraocular inflammation in an endotoxin-induced uveitis (EIU) model in ... -
Experimental Chronic Toxoplasmosis Model in Mice: Brain Lesions and Related Behavioral Changes
(Galenos Yayincilik, 2012)Objective: In this study, it is aimed to constitute a chronic toxoplasmosis model using toxoplasma gondii (T. gondii) ME49 strain that is supposed to produce tissue cysts, to compare healthy and infected mice in terms of ... -
Central nervous system and skull malformations associated with Bovine Viral Diarrhea Virus in a calf
(Ankara Univ Press, 2012)In this study, cranial anomalies, hydranencephaly and cerebellar hypoplasia were reported macroscopically, microscopically and immunohistochemically in a calf. A relationship between Bovine Viral Diarrhea Virus infection ... -
Deneysel kronik toksoplazmoz fare modeli: Beyin lezyonlarının davranış değişiklikleri ile ilişkilendirilmesi
(2012)Amaç: Bu çalışmada; kist oluşturan T. gondii ME 49 suşu ile enfekte farelerde oluşan anksiyete ile ilişkili davranış değişiklikleri ve beyin lezyonlarıyla ilişkisinin araştırılması amaçlanmıştır. Yöntem: Uygulama öncesi ... -
Reactivated and clinical Toxoplasma gondii infection in young lambs: Clinical, serological and pathological evidences
(Elsevier Science Bv, 2012)In this study, fatal toxoplasmosis with severe neurological clinical signs was evaluated in 20 lambs of a sheep flock containing 90 Akkaraman sheep, 60 lambs and 3 rams. The clinical signs in infected lambs (n = 20) included ... -
Hepatogenous photosensitization in Akkaraman lambs: special emphasis to oxidative stress and thrombocytopenia
(Ankara Univ Press, 2013)In this study, a total of 24 Akkaraman lambs with clinical signs that are reminiscent of photosensitization composed the experimental group (Group I). Additional 10 healthy lambs were included as controls (Group II). We ... -
Hepatic stellate cells increase in Toxoplasma gondii infection in mice
(Bmc, 2013)Background: Toxoplasma gondii is a ubiquitous protozoan parasite that can infect humans and animals. The severity of toxoplasmosis varies according to the immune status of the individual, parasite strain, and host species. ... -
Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds
(Informa Healthcare, 2013)Bovine chondrocytes were seeded into scaffolds of a high molecular weight chitosan and alginate with a pore size of 50-350 mu m with or without catechin. In polymerase chain reaction (PCR), unlike type II, collagen type I ... -
A new approach to Neospora caninum infection epidemiology: neosporosis in integrated and rural dairy farms in Turkey
(Scientific Technical Research Council Turkey-Tubitak, 2014)Both cattle and dogs were examined in modern and rural dairy farms that had a history of abortion over 5%. The blood samples were collected from 427 aborted cattle and the sera were tested using a commercial ELISA test ... -
Effects of ozone therapy and taurine on ischemia/reperfusion-induced testicular injury in a rat testicular torsion model
(Tubitak Scientific & Technical Research Council Turkey, 2014)Background/aim: To investigate the effect of ozone and/or taurine treatment comparatively on testicular damage due to ischemia/reperfusion (I/R) injury in an experimental torsion model in rats. Materials and methods: Adult ... -
Ginkgo Biloba Extract (EGb 761) Protects The Mice Brain Against Fluoride-Induced Oxidative Stress
(Parlar Scientific Publications (P S P), 2014)The aim of this study was to investigate the effects of Ginkgo biloba extract (EGb 761) on oxidative stress and the histopathological changes in brain tissues of mice exposed to fluoride administration. A total of 24 mice ... -
The Ocular Endothelin System: A Novel Target for the Treatment of Endotoxin-Induced Uveitis With Bosentan
(Assoc Research Vision Ophthalmology Inc, 2014)PURPOSE. We compared the anti-inflammatory effects of bosentan and dexamethasone in endotoxin-induced uveitis (EIU). METHODS. Endotoxin-induced uveitis was induced by subcutaneous injection of lipopolysaccharide (LPS, 200 ... -
Astrocytes, microglia/macrophages, and neurons expressing Toll-like receptor 11 contribute to innate immunity against encephalitic Toxoplasma gondii infection
(Pergamon-Elsevier Science Ltd, 2014)Toll-like receptor 11 (TLR11) is a specific receptor for Toxoplasma gondii and uropathogenic Escherichia coli and has recently been identified in the mouse brain. In the present study, TLR11 gene expression was measured ... -
Protective effect of resveratrol on sodium fluoride-induced oxidative stress, hepatotoxicity and neurotoxicity in rats
(Pergamon-Elsevier Science Ltd, 2014)Protective effect of resveratrol on sodium fluoride-induced oxidative stress, hepatotoxicity and neurotoxicity were studied in rats. A total of 28 Wistar albino male rats were used. Four study groups were randomly formed ... -
What is the role of bosentan in healing of femur fractures in a rat model?
(Springer Japan Kk, 2015)The purpose of this study was to examine the effects bosentan (which is a strong vasoconstrictor) on bone fracture pathophysiology, and investigate the roles of the nonselective endothelin 1 receptor blocker bosentan on ... -
Increased Expressions of ADAMTS-13, Neuronal Nitric Oxide Synthase, and Neurofilament Correlate with Severity of Neuropathology in Border Disease Virus-Infected Small Ruminants
(Public Library Science, 2015)Border Disease (BD), caused by Pestivirus from the family Flaviviridae, leads to serious reproductive losses and brain anomalies such as hydranencephaly and cerebellar hypoplasia in aborted fetuses and neonatal lambs. In ... -
Nitric oxide production increases during Toxoplasma gondii encephalitis in mice
(Academic Press Inc Elsevier Science, 2015)Toxoplasma gondii is an intracellular parasite with the potential of causing severe encephalitis among immunocompromised human and animals. The aim of this experimental study was to investigate the immunomodulatory and ... -
The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus
(Springer, 2015)Purpose The aim of this study is to show the effect of a new mechanism on endothelin (ET) receptors in the physiopathology of diabetes-related pulmonary injury. We tested the hypothesis that dual ET-1 receptor antagonism ...